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UCL Bioprocess Engineering Leadership Industrial Doctorate Training Centre

EPSRC funded EngD Opportunities

The Advanced Centre for Biochemical Engineering PhD StudentsThe UCL Advanced Centre for Biochemical Engineering trains bioprocess engineering leaders of the future who will underpin the translation of new scientific advances into safe, selective and manufacturable therapies for what are often currently intractable conditions, but at affordable costs. To achieve this we embed our Engineering Doctorates (EngDs) within the vibrant research community at UCL and with internationally leading industry collaborators.

The Course
An Engineering Doctorate (EngD) is a higher degree providing engineers and scientists with full research training at the life sciences interface that is relevant to bioprocessing and related technologies. The training programme equips students with the requisite knowledge and terminology in current life science subjects to allow them to explore topics in their own research project under direction from their supervisory team.

Students come from a wide range of disciplines including Life Sciences, Engineering, and Physical Sciences , with interests in bioprocess research at the interfaces of biochemistry, chemical and biochemical engineering, mechanical engineering, chemistry, physics, and computational sciences. Research topics span bioprocess design, mammalian cell culture, stem cell processing, protein engineering, bioanalytics, formulation, process automation, microfluidics, process and cost modelling, biocatalysis and synthetic biology.

Each student admitted to the IDTC will complete a four year EngD. The doctoral research is complemented by taught courses and case studies designed to familiarise the student with bioprocessing topics, the life sciences interface and also the business and regulatory environment.

Taught topics are all delivered by an international lecturing team and include:
Bioprocess Engineering Leadership Industrial Doctorate Training Centre
  • Speed from discovery to benefit: using small mimics and mathematical models enhances the precision and rate of process development.
  • Harnessing genomics: directed evolution and metabolic engineering can deliver efficient synthesis of complex drugs and improved catalysts.
  • Making the outcome affordable: business approaches coupled with engineering paradigms offer new healthcare opportunities.
  • Processing of complex materials: epitomised by the use of human proteins and stem cells for therapy where the challenge is to process materials of increasing complexity to make them available to all who need them.
  • Environment and sustainability: exploiting environmentally benign biological catalysts allows replacement of toxic solvents and presents opportunities to make significant industrial improvements.
Individual Projects
The student's individual research project for the EngD will be selected from a wide range of opportunities which reflect the Department's global health agenda.

Examples
John examined issues of scale up for packed bed chromatographic processes and established a new framework for the prediction of performance at large scale. Sponsored by BioPharm Services John took up a project engineering position with Jacobs Engineering and is now working extensively in Switzerland on a large biotech project.

Naveraj was sponsored by the Hazards Evaluation Laboratories (HEL) where she investigated the ability of small-scale systems to mimic the full-scale performance of bioreactors. She has remained in the academic field as a researcher on a large Technology Strategy Board (TSB) grant which is considering the use of miniaturised systems for the rapid development of bioprocesses.

For more case studies see
www.ucl.ac.uk/biochemeng/students/casestudies

EngD sponsors to date include:
Biochemical EngineeringAvecia Biologics, The Automation Partnership, BioPharm Services, Biovex, BPL, Eli Lilly, Evotec, GE Healthcare, GSK, HEL, HPA, Ingenza, InterCell, Lonza Biologics, MedImmune, Merck, Moorfields Eye Hospital, Novo Nordisk, Onyvax, Pall Europe, Pfizer, Plasticell, Prometic, Smith & Nephew, UCB Celltech, Unilver and Westfalia Separator.
Projcet Selection
Discussion between student, the academic supervisors and the sponsors are crucial to the selection of a world-class research and training experience for each doctoral candidate.

Students in our internationally renowned Department make use of the recent £30m of investment in comprehensive and unique facilities including a fully equipped pilot-plant, a micro-engineering facility with robotics systems and advanced regenerative medicine labs. All of these are underpinned by state-of-the-art analytical equipment.

Upon completion of the EngD excellent and diverse career routes are available for our sought after UCL biochemical engineers.

Bioprocess Engineering PhD ResearchHow do I apply?
Initial enquiries to:

Mrs Jana Small
The Advanced Centre for Biochemical Engineering
University College London
Torrington Place
London WC1E 7JE

Tel:
0207 679 4411
Email: jana.small@ucl.ac.uk