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  Understanding and mitigating blast injuries- Blast Biology


   Royal British Legion Centre for Blast Injury Studies

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Dr S Rankin  No more applications being accepted  Funded PhD Project (European/UK Students Only)

About the Project

Immediate PhD research opportunities in the Royal British Legion Centre for Blast Injury Studies at Imperial College London

This is a call for the inaugural cohort of PhD studentships based in the Royal British Legion Centre for Blast Injury Studies at Imperial College London (CBIS). The Centre has been established following a multimillion pound donation by the Royal British Legion, and presents a unique opportunity for successful candidates to work with a collaborative team of military and civilian clinicians, scientists and engineers.

Successful students will undertake research leading to platform and application technologies with the central aim of understanding and mitigating blast injuries, commonly caused by improvised explosive devices (IEDs). The cohort will benefit from a continuous education program running alongside the research program. Four specific appointments will be made, while a further two studentships may be allocated depending on the quality of candidates.

• Blast Biology: High compression waves arising from IEDs can cause severe damage to the lung. Blast lung is the most common cause of death in people who initially survive an explosion. This PhD project will investigate the effect of high compression waves on lung at a molecular, cellularand tissue level. Interested candidates seeking further information on the project should contact: Prof Sara Rankin ([Email Address Removed]).

It is expected that candidates will come from a range of disciplines, but must have an outstanding undergraduate background, and be able to demonstrate expertise in experimental, analytical and computational work.

All applicants should submit a formal application with the Department of Bioengineering through the Imperial College London online application system, clearly marking the application for the Centre for Blast Injury Studies, as well as emailing a CV and cover letter in PDF format to [Email Address Removed]

Funding for the PhD studentships includes a stipend at the standard rate, fees and running costs.

Applicants must be eligible for HOME/EU fees status.

The closing date for applications is: 1st May 2012. Shortlisted applicants will be contacted
shortly after the 8th May and invited for interview in mid to late May.

For further information on the centre please visit: www.imperial.ac.uk/blastinjurystudies

For further information on postgraduate study and to submit an application please visit:
www.imperial.ac.uk/pgaf

Committed to equality and valuing diversity. We are also an Athena Bronze SWAN Award winner, a Stonewall Diversity Champion and a Two Ticks Employer.

Project supervisors

Career overview

Professor Sara Rankin is the Professor of Leukocyte and Stem Cell Biology at the National Heart and Lung Institute, Imperial College London. She obtained a first-class honours degree and a PhD in Pharmacology from King''s College London. Following her studies, she undertook postdoctoral positions in the Department of Medicine at the University of California, San Diego, and at the Imperial Cancer Research Fund, now known as Cancer Research UK. In 1995, Professor Rankin joined the Leukocyte Biology Section of the Institute with a Wellcome Trust Career Development Award. She later secured a Wellcome Trust University award and has since established herself as a Professor in Leukocyte and Stem Cell Biology. Her research primarily focuses on the role of the bone marrow in inflammatory diseases and the molecular mechanisms that regulate the exit of leukocytes and stem cells from the bone marrow. Current research areas include neutrophil clearance by the bone marrow, the molecular mechanisms regulating the mobilisation of haematopoietic, endothelial, and mesenchymal progenitor cells, the trafficking of mesenchymal stem cells in vivo, and the role of endothelial progenitor cells in angiogenesis in models of allergic airways inflammation. Professor Rankin currently holds grants from several organisations, including the Wellcome Trust, the European Commission, the British Heart Foundation, the Medical Research Council, and various industrial collaborators. In addition to her research, she was awarded a Certificate in Advanced Studies in Learning and Teaching in 2001 and serves as a postgraduate tutor and Deputy Head of Postgraduate Studies for the National Heart and Lung Institute. Professor Rankin is also the Institute lead for Outreach and participates in numerous public engagement and outreach activities. She is a member of the Education Committee for the British Pharmacological Society and is a Fellow of the Society of Biology. Professor Rankin has been involved in organising significant meetings, including ''The Neutrophil in Immunity'' in Quebec in 2012 and the ''Pharmacology of Stem Cell Research & Regenerative Medicine'' in association with the British Pharmacological Society Winter Meeting.


Research interests

Professor Rankin''s research focuses on understanding the impact of the bone marrow in inflammatory diseases and elucidating the molecular mechanisms regulating the exit of leukocytes and stem cells from the bone marrow. Current research areas include neutrophil clearance by the bone marrow, molecular mechanisms regulating the mobilisation of haematopoietic, endothelial, and mesenchymal progenitor cells, trafficking of mesenchymal stem cells in vivo, and the role of endothelial progenitor cells in angiogenesis in models of allergic airways inflammation. Professor Rankin currently holds grants from the Wellcome Trust, The European Commission, the British Heart Foundation, the Medical Research Council, and industrial collaborators.

View Prof. Sara Rankin's profile