19 June, 2013
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Monitoring and control of sublimation within the freeze drying process.
School of Life & Health Sciences
Dr A J Ingham
No more applications being accepted
Funded PhD Project (European/UK Students Only)
This research project has funding attached. Funding for this project is available to citizens of a number of European countries (including the UK). In most cases this will include all EU nationals. However full funding may not be available to all applicants and you should read the full department and project details for further information.
PhD Research Project
For an Engineering BSc/MSc Student, based in the School of Pharmacy,
School of Life & Health Sciences, Aston University, Birmingham
Applications are invited for a talented Engineering Post Graduate with an interest in interdisciplinary science to work on a challenging project to implement Process Analytical Technology (PAT) to improve the control of drug formulation processing, a critical area for the pharmaceutical industry with applications in many manufacturing sectors. Study will require your skills across fast prototyping, mechanical modification of equipment and electrical control but you will be learn about vacuum and compression systems for control of high vacuum and very low temperature systems that require control.
The demand for the application of Process Analytical Technology (PAT) was initiated by the Food and Drug Administration (FDA) to control drug processing. The aim is to give equipment its own control over the processing of drugs so it can automatically improve the processing through systems engineering. Industry has, however, struggled to implement these recommendations. The candidate will work in a leading academic group in the UK in collaboration with a major worldwide pharmaceutical company developing PAT initially with their own in house system to first develop prototype sublimation monitors. This will extend to the production level by the end of the period of study with the potential of commercial scale manufacture.
The PhD will be based at Aston University for three years with an additional 1 year industrial research training with Biopharma Technology, one of the leaders in research for freeze drying worldwide, and its sister company BPS with experience of industrial freeze drier design and specification. The ability to gain pharmaceutical engineering experience across the full spread of technology can be expected with additional training in Good Manufacturing and Good Laboratory practice being provided.
Study will be within the School of Pharmacy (all applications must be through the School of Life and Health Sciences).
● Eligibility details: http://www.bbsrc.ac.uk/web/FILES/Guidelines/studentship_eligibility.pdf
Therefore Overseas Students are not eligible to apply.
● Eligible Applicants should hold at least a Bachelor (Hons.) Degree in either First or Upper Second Class Or hold an MSc in Engineering or Engineering related subject.
● EU Applicants will need to demonstrate adequate proficiency in English Language skills, with a minimum score of 620 (260 minimum in computer test) in TOEFL or IELTS with minimum marks of 6.5 in each section and an overall band of 7.0.
● To apply please complete the online application form at http://www1.aston.ac.uk/lhs/research/postgraduate-research/apply/ and please quote the reference
‘BBSRC-Ingham’ on all applications.
● The Closing Date for Applications is: Friday, 1st June 2012.
The studentship comprises a BBSRC maintenance stipend for the student (currently £16,090 per annum tax free) and payment of Home/EU tuition fees. The studentship is available under the BBSRC funding model for the duration of your registration, subject to a satisfactory progress review at the end of the first year. We anticipate either a July or October 2012 Registration.
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