Take our PhD survey
Take our PhD
survey for the
* or equivalent in Euros or US Dollars
23 May, 2013
Browse By Subject
Browse By Region
Professional Development (CPD)
PostDoc & PhD Jobs
PhD Research Project
This project is no longer listed in the FindAPhD database
and may not be available.
Click here to view other PhD studentship opportunities at University of Bristol.
Engineering and structural characterisation of photovoltaic proteins for applications in (photo) synthetic biology
University of Bristol
School of Biochemistry
Dr M R Jones
Dr P Race
No more applications being accepted
Competition Funded PhD Project (European/UK Students Only)
This research project is one of a number of projects at this institution. It is in competition for funding with one or more of these projects. Usually the project which receives the best applicant will be awarded the funding. The funding is available to citizens of a number of European countries (including the UK). In most cases this will include all EU nationals. However full funding may not be available to all applicants and you should read the full department and project details for further information.
PhD Research Project
Photosynthetic reaction centres are nature’s nanoscale solar batteries, and are attracting growing interest as power modules for applications in synthetic biology. A central aim of the research in Mike Jones’ laboratory is to develop the purple bacterial reaction centre as a photovoltaic material for use in a variety of nanoscale and macroscale contexts, including biosolar cells, biosensors, biocomputing and new molecular photocatalysts. A key underpinning technology for all of these applications is the interfacing of natural photosynthetic proteins with man-made materials that act either as electrodes or as solid supports for catalysis. Development of this technology requires re-engineering of protein surfaces that have evolved to facilitate natural protein-protein and protein-ligand interactions into surfaces that interface in a specific, stable and productive manner with man-made materials. One promising approach is to exploit protein sequence motifs that show selective affinity for one of a variety of common electrode materials such as TiO2, ZnO, SiO2, carbon nanotubes, platinum and gold.
The purpose of the project will be to engineer such peptide sequences into the purple bacterial reaction centre, either into surface-exposed loops or as N- or C-terminal extensions, to examine the resulting affinity of the protein for specific materials, to assess the photovoltaic and photocatalytic capacity of the engineered proteins and, in conjunction with the neighbouring Paul Race laboratory, to examine the structures of the engineered proteins through X-ray crystallography. This project will provide training in computer modelling of protein structure, molecular biology, membrane protein biochemistry,
microbiology, X-ray crystallography, photoelectrochemistry and steady-state and time-resolved spectroscopy. The project will form part of a network of collaborations with biochemists, chemists, physicists, engineers and materials scientists that encompasses laboratories in the UK, Netherlands, Italy, France, Hungary and Poland, and the appointee will have opportunities to visit these groups to gain first hand experience of specialist techniques.
Keywords: membrane protein, photochemistry, reaction center, photovoltaics, photocatalysis, bio-solar cells, bioenergy
Web Page http://www.bch.bris.ac.uk/staff/mrj.html
Competitive funding for UK/EU students via the BBSRC SWDTP is currently available for the following project:
Engineering and structural characterisation of photovoltaic proteins for applications in (photo) synthetic biology. Dr Jones, Dr Race
For an opportunity to undertake a SWDTP funded project with this supervisor, please visit the SWDTP website:
When applying online, please ensure you include "SWDTP Funded Project" in the "Research Details" section of the online form.
Tan, S.C., Crouch, L.I., Mahajan, S., Jones, M.R. and Welland, M.E. (2012) Tuning the open circuit voltage of photoprotein-based photoelectrochemical cells by manipulation of the vacuum potential of the electrolyte. ACS NANO 6, 9103-9109
Tan, S.C., Crouch, L.I., Jones, M.R. and Welland, M.E. (2012) Generation of alternating current in response to discontinuous illumination by novel photoelectrochemical cells based on photosynthetic proteins. Angewantde Chemie International Edition 51, 6667–6671
den Hollander, M.-J., Magis, J.G., Fuchsenberger, P., Aartsma, T.J., Jones, M.R. and Frese R.N. (2011) Enhanced photocurrent generation by photosynthetic bacterial reaction centers through molecular relays, light-harvesting complexes and direct protein-gold interactions. Langmuir 27, 10282-10294
Gibasiewicz, K., Pajzderska, M., Potter, J.A., Fyfe, P.K., Dobek, A., Brettel, K. and Jones, M.R. (2011) Mechanism of recombination of the P+HA- radical pair in mutant Rhodobacter sphaeroides reaction centers with modified free energy gaps between P+BA- and P+HA-. Journal of Physical Chemistry B 115, 13037-13050
Like This PhD?
Add To Shortlist
PhD Provider Info
Visit Provider Website
All PhDs in this Dept
Send to a Friend
Printer Friendly Page
View A Larger Map
Exploitation of polyubiquitin-binding proteins to identify novel proteins that control innate immunity
University of Dundee
MRC Protein Phosphorylation and Ubiquitylation Unit
Using structural biology tools to understand molecular mechanisms in the ubiquitin system and cancer biology
University of Nottingham
School of Pharmacy
EngD - Development of a thin-film photovoltaic cell division and interconnection scheme
School of Engineering & Physical Sciences
Research in organic photovoltaic devices
University of Sheffield
Department of Physics and Astronomy
Postgraduate Study Fair
MANCHESTER, 20 NOVEMBER 2013
Postgraduate Study & MBA Fair
LONDON, 30 JANUARY 2014
Like FindAPhD for news, events & competitions
Follow us on Twitter
Find A PhD
All rights reserved
Search for PhDs
PhDs by Subject
PhDs by Institution
PhDs by Region
Info for Students
PhD Study Guide
PhDs in the UK
PhD Funding Guide
Postgraduate Advice Forum
Postgraduate Email Updates
Info for Advertisers
Advertise a PhD
Banner & Buttons
Advertisers T & Cs
PostDoc & PhD Jobs
The Science Registry Ltd
, Sellers Wheel, 151 Arundel Street, Sheffield, S1 2NU, United Kingdom. Tel +44 (0) 114 268 4940 Fax: +44 (0) 114 268 5766
Clicking here will add this PhD to your PhD shortlist.
Your PhD shortlist allows you to easily browse, email & save projects and programmes.
Enquiry by Telephone
click to proceed
Enquiry by Email
click to proceed
Apply Online NOW!
click to visit
Add to and from your shortlist
click to add/remove
Click here to view the items added to your shortlist.