Enzyme-Responsive Hydrogels for Diagnostics, Delivery and Regenerative Medicine

The project involves collaboration with Dr Stephen King (ISIS neutron source) and Dr Stan Botchway (CLF, Central Lasers Facility) and is co-funded by the STFC Futures initiative.

The healthcare challenges associated with an aging population, regenerative medicine and cancer require new diagnostic and drug delivery systems, and substrates for cell growth and differentiation in tissue engineering. You will investigate the self-assembly and structure of novel, water-based, biocompatible, polymer hydrogels. The hydrogels will be functionalised with peptides that will serve as substrates for specific enzymes, including those associated with Alzheimer's and the inflammation associated with this condition, and those targeting certain cancers. In addition, gels will be developed with applications in tissue engineering, in particular, for wound healing of the skin. You will be required to spend time during your studentship at the Harwell Science and Innovation Campus, approximately 30 miles from Reading.

Applicants should hold a minimum of a UK Honours Degree at 2:1 level or equivalent in a relevant subject. Please note that due to restrictions on the funding this studentship is for UK/EU applicants only.

Please quote the reference GS13-11’ in the ‘Scholarships applied for’ box which appears within the Funding Section of your online application.