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  Investigating the genetic identity and biological phenotype of HIV-1 founder viruses


   Public Health

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  Dr T Mbisa  No more applications being accepted  Funded PhD Project (European/UK Students Only)

About the Project

The prognosis of HIV-infected individuals has improved significantly since the introduction of highly active antiretroviral therapy nearly two decades ago. However, limited approaches exist for preventing HIV transmission or eradicating the virus from infected individuals. In part, this is because little is known about early events in HIV infection that result in the establishment of viral infection and persistence. Both viral and host factors are thought to play a significant role. This PhD project will aim to identify and characterize the genetic and biological characteristics of a UK cohort of HIV founder viruses and help the understanding of early events in transmission of HIV. This is a collaborative project bringing together the expertise in host innate immune response to HIV (Prof. Greg Towers, UCL) and phenotypic and genotypic characterization of HIV (Dr. Tamyo Mbisa, PHE). Applications are sought from highly motivated individuals with a first or upper second class honours undergraduate degree or MSc in an appropriate life science subject e.g. biology, biomedical science. The candidate will have experience in laboratory-based research e.g. an honours project or vacation studentship and preferably experience in molecular biology. The studentship is open to UK and EU applicants and the student will be registered with the Graduate School in the UCL School of Life and Medical Sciences.

Funding Notes

EU applicants must demonstrate a relevant connection to the UK through ordinary residence. As a UK public funded body, PHE cannot fund applicants from outside the EU.
Please apply by sending your CV and a covering letter explaining why you are suited to undertaking this project to: [Email Address Removed]