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  The role of miR-30 family members in signalling in cancer and cardiomyocytes.


   BHF Centre of Research Excellence

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  Prof J Stebbing, Dr L Castellano  No more applications being accepted  Funded PhD Project (European/UK Students Only)

About the Project

Supervisors: Professor Justin Stebbing, Dr Leandro Castellano and Dr Alexander Lyon

Applications are invited for this MRes/PhD studentships within the BHF Centre of Research Excellence at Imperial College London, one of six starting October 2015. The studentships are funded through a training grant from the BHF on a tax-free bursary starting from £17,500 per annum. Tuition fees will be paid at the Home/EU rate. There is no provision for overseas student fees.

Imperial College London’s BHF Centre of Research Excellence, sponsored by the UK’s leading charity for pioneering research into heart disease, is an established cross-disciplinary venture. Our aim has been to foster a unique collaborative research environment that draws on Imperial’s world class reputation in cardiovascular science, engineering and collaborating physical sciences.

Project summary
Our work aims to combine bioinformatics, wet laboratory approaches with an investigation into how regularly used anti-cancer drugs can affect the heart. In particular, we aim to look at non-coding RNA molecules to understand and establish the role they play, connecting cardiac to cancer cell function. We wish here to build on our current data which demonstrates at microRNA family is induced by chemotherapy and targets the beta-adrenergic receptor.

Students will first undertake the MRes in Biomedical Research, a full-time master’s course, in which we form the Cardiovascular Science, Technology and Medicine (C/STEM stream), with projects and taught classes provided by BHF Centre members. Our trainees receive cross-disciplinary supervision, with at least two supervisors drawn from different Faculties or Departments. Upon successful completion of the MRes year, students will progress to a 3 year PhD training programme in an aligned area.

Imperial College London provides excellent opportunities for research student training. All students benefit from a full programme of training in research and transferable skills organised through the Graduate School, the quality of which has been recognised several times at the Times Higher Education (THE) Awards.

How to Apply
Applicants must hold, or expect to obtain, a first or upper second-class honours degree or equivalent in an appropriate subject from a recognised academic institution. To apply, please send your CV, the names and addresses of at least two academic referees and a personal statement of no more than 1,000 words explaining your interest in a cross-disciplinary approach to cardiovascular science relevant to the project to Dr Gunvanti Goding by email on [Email Address Removed] Please note that candidates must fulfil College admissions criteria.

Please assume that your application has not been successful if you have not heard from us within a month of the closing date.

Closing date for all applications: 12 January 2015

Interviews will be held at the end of January 2015

Website: http://www.imperial.ac.uk/nhli/

Committed to equality and valuing diversity. We are also an Athena Silver SWAN Award winner and a Stonewall Diversity Champion.

 About the Project