University of Nottingham Cancer Biology PhD Projects, Programmes & Scholarships

We have 6 University of Nottingham Cancer Biology PhD Projects, Programmes & Scholarships

Structure and function of enzyme complexes involved in post-transcriptional gene regulation

University of Nottingham School of Pharmacy

Many proteins in human cells function as part of high molecular weight multi-subunit assemblies. The structure and function of such large molecular machines is often difficult to characterise due to their complexity, low abundance and structural dynamics. Read more

Supervisor: Dr G S Winkler

Year round applications PhD Research Project Self-Funded PhD Students Only

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Role of BTG1 and BTG2 in acute lymphocytic leukaemia and diffuse large B-cell lymphoma

University of Nottingham School of Pharmacy

Acute lymphocytic leukaemia (ALL) and diffuse large B-cell lymphoma (DLBCL) is often associated with small deletions of or point mutations in the highly related BTG1 or BTG2 genes. Read more

Supervisor: Dr G S Winkler

Year round applications PhD Research Project Self-Funded PhD Students Only

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Discovery and profiling of small-molecule inhibitors of cellular nuclease enzymes

University of Nottingham School of Pharmacy

Nuclease enzymes are non-traditional drug targets that attract an increasing amount of interest as potential targets relevant for a variety of therapeutic areas including infection, cancer and bone disease. Read more

Supervisor: Dr G S Winkler

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding transcription factor complexes controlling endothelial cell quiescence and escape from quiescence

University of Nottingham Division of Cancer and Stem Cells

Endothelial cell proliferation and lymphatic cell proliferation is initiated during angiogenesis and lymphangiogenesis respectively and are both regulated by the VEGF signalling pathway. With some exceptions, endothelial and lymphatic cells in healthy individuals are quiescent and do not proliferate. Read more

Supervisors: Dr S Jayaraman , Prof K Gaston, Dr AB Benest

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the communication between cancer cells and cells in the tumour microenvironment to improve our understanding of epigenetic regulatory mechanisms and identify new targets for cancer therapy

University of Nottingham School of Medicine

It is well-established that the molecular mechanisms controlling gene expression are disrupted in cancer cells and work in this area has laid the foundations for targeted cancer therapies. We are interested in the regulatory pathways that control cell proliferation and cell migration and the events that disrupt this control in multiple types of cancer. Read more

Supervisors: Prof K Gaston, Dr S Jayaraman

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding transcription factor complexes in endothelial quiescence

University of Nottingham Division of Cancer and Stem Cells

Endothelial cell proliferation and lymphatic cell proliferation known as angiogenesis and lymphangiogenesis respectively are both regulated by ligands in the VEGF signalling pathway. Read more

Supervisors: Dr S Jayaraman , Prof K Gaston, Dr AB Benest

Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

We have 6 University of Nottingham Cancer Biology PhD Projects, Programmes & Scholarships

University of Nottingham Cancer Biology PhD Projects, Programmes & Scholarships

We have 6 University of Nottingham Cancer Biology PhD Projects, Programmes & Scholarships

University of Nottingham

Structure and function of enzyme complexes involved in post-transcriptional gene regulation

Role of BTG1 and BTG2 in acute lymphocytic leukaemia and diffuse large B-cell lymphoma

Discovery and profiling of small-molecule inhibitors of cellular nuclease enzymes

Understanding transcription factor complexes controlling endothelial cell quiescence and escape from quiescence

Investigating the communication between cancer cells and cells in the tumour microenvironment to improve our understanding of epigenetic regulatory mechanisms and identify new targets for cancer therapy

Understanding transcription factor complexes in endothelial quiescence

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