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Dept/School School of Chemistry, University of St Andrews
Project Supervisor(s) Dr G Florence
Funding Availability
Directly Funded Project (UK Students Only) - See Funding Key for more detailsDirectly Funded Project (UK Students Only)
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PhD Studentship: Organic Chemistry: Natural Product Synthesis/Organic Materials

Research in the Florence group is concerned with the development of new methods and
strategies for the practical synthesis of rare bioactive natural products.The targets we
select represent an exciting range of secondary metabolites that display startling
bioactivity in preliminary biological screening, but due to their scarcity, require practical
synthetic routes to enable structure determination and allow further biological evaluation
of their properties in the quest for new therapeutic agents. This project supported by the
EPSRC-Pharma initiative is focussed on the synthesis and structure elucidation of
leiodolide A, a potent and selective cytotoxic agent towards a number of human cancers.
The project is supported for 4 years with a six month industrial placement with
AstraZeneca.

For further information on this opportunity and informal enquiries please contact Dr
Gordon Florence as soon as possible (gjf1@st-andrews.ac.uk).

Potential applicants are welcome to arrange to visit St Andrews. Please see:http://www.st-
andrews.ac.uk/PGadmissions.html for the application procedure or e-mail chempg@st-
andrews.ac.uk for more information.


Funding Notes
Funding is only available to applicants from the UK only

Research Assessment Exercise (RAE) 2008 Results

Unit of Assessment: ChemistryWhat is the RAE?
FTE Category A Staff Submitted4*3*2*1*U/C
3330%40%30%0%0%
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