This project will examine the evolution, genetic diversity and population structure of the fission yeast Schizosaccharomyces pombe, using genome-scale approaches. S. pombe is an important model organism, with a well-annotated genomes and well described cellular biology. Analysis of the evolution of its genome will enrich our understanding the genome, cellular biology and ecology of this species. An exciting possibility is that new Schizosaccharomyces species could be discovered that will be useful for comparative genomics. This project will involve study of wild yeast strains; initially species/strain verification by PCR and then next generation sequencing of the genomes, followed by population genetic and evolutionary analysis. A successful PhD candidate will require a basic knowledge of a scripting language (or a willingness to learn), and will be interested in genetics, evolution, and/or genome biology. Ability to conduct wet-lab experiments is preferred, but not essential.
Funding Notes This project will be subject to open departmental competition, is funded at standard NERC rates and is subject to NERC eligibility requirements (see details at: http://www.nerc.ac.uk/funding/available/postgrad/eligibility.asp). Full studentships (stipend and tuition fees) are normally only available to UK citizens and to non-UK EU nationals who have been resident in the UK (including time spent in education) for the three years prior to the start date. Minimum UCL academic entry requirements apply (ie. BSc Upper 2nd Class Honours in a relevant subject). To apply send an email outlining your interests and experience, including a CV and at least two academic references.
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