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| Dietary phytonutrients and vascular cell function | |||||||||||||
The studentship will investigate whether plant derived dietary compounds enhance nitric oxide synthesis and antioxidant gene expression in human vascular endothelial cells to elucidate the mechanisms by which these compounds can improve vascular reactivity and ameliorate age related vascular diseases. Findings from this study should provide novel and valuable information for planning future trials to address whether phytonutrient supplementation can improve vascular function in older subjects and those with existing cardiovascular risk factors. This area of research is particularly relevant to the Next Generation Anti-Ageing platform (NGAA) of Unilever Discover, which is committed to identifying novel areas of research to advance our understanding of the underlying mechanics of ageing. The findings from this study should drive the delivery of novel research projects from the NGAA platform to the Cardiovascular Health field expanding on our knowledge of antioxidant gene and redox signalling pathways and identifying potential new molecular targets to maintain vascular health in ageing. This 4 year studentship is in collaboration with Dr Mark Fowler at Unilever and will include a placement at Unilever during the studentship to provide additional research training in an industrial environment. To apply, please email a full CV with relevant academic and skills details to richard.siow@kcl.ac.uk For further information please email richard.siow@kcl.ac.uk Applications will be accepted until the position is filled Funding Notes Stipend: Approx £18,500 per year Further information: http://www.kcl.ac.uk/schools/health/study/studentships/cardiovascular/siow.html |
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