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| Modelling of synaptic integration in cortical neurons | ||||||||||||
This MRC Capacity Building Ph.D. studentship in the Department of Physiology, Development and Neuroscience, University of Cambridge, aims to study the encoding of information in cortical pyramidal neurons and interneurons, using detailed biophysical computational modelling of ion channel gating and electrical current flow in these cells, combined with real-time computational approaches (conductance injection / dynamic clamp) experimentally. The goal is to understand how patterns of synaptic input are encoded in action potential timing and shape, during network oscillations. This opportunity will be particularly suited to a student with an undergraduate degree in neuroscience, but with programming experience, or having an undergraduate degree in physics, computer science or engineering, who is interested in neuroscience. Funding Notes Directly funded project (UK students only) Funding: 3 years studentship, MRC studentship eligibility requirements apply (see http://www.mrc.ac.uk/fundingopportunities/applicanthandbook/studentships/eligibility/index.htm ). EU students from outside the UK qualify for a “fees only” award. Morita, K., R. Kalra, K. Aihara and H. P. C. Robinson (2008). "Recurrent synaptic input and the timing of gamma-frequency-modulated firing of pyramidal cells during neocortical "UP" states." J Neurosci 28(8): 1871-81. |
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