We have 1,718 1 3 PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

Background. Fragment-based methods are established for the identification of lead compounds in drug discovery.[1] Fragments are small molecules (molecular weight ~150-300) which bind weakly to proteins. Read more

Supervisor: Prof P O'Brien

Year round applications PhD Research Project Self-Funded PhD Students Only

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Countering the proteinase-activated receptor 1 (PAR-1) pro-tumour phenotype using a novel nanotherapeutic approach

Queen’s University Belfast School of Pharmacy

Proteinase-activated receptor 1 (PAR1) is a G-protein coupled receptor (GPCR) expressed on a number of cell types, and is activated by serine proteases such as thrombin, plasmin and activated protein C. Read more

Supervisor: Dr J Coulter

Year round applications PhD Research Project Self-Funded PhD Students Only

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Emulating randomized trials in observational data to determine ethnic differences in the effects of type 2 diabetes treatments

Queen Mary University of London Barts and The London School of Medicine and Dentistry

Applications are invited from graduates with an MSc (Distinction) or equivalent to work within the Wolfson Institute of Population Health. Read more

Supervisor: Dr R Mathur

31 March 2023 PhD Research Project Funded PhD Project (Students Worldwide)

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Self Funded PhD Project: Studies on the Design, Synthesis and Biological Evaluation of a Novel Bioactive Indane Scaffold

Technological University Dublin Graduate Research School Office

A wide range of bioactive indane based scaffolds are employed clinically as treatment of many disease states, including inflammatory [1], cancer [2] and neurological conditions [3] and also in the treatment of HIV [4]. Read more

Supervisor: Dr TZ Zhang

Year round applications PhD Research Project Self-Funded PhD Students Only

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Moorfields Eye Charity funded 3-Year PhD Studentship: Role of Galectin-1 in vascular dysfunction and leakage associated with retinopathies

University College London Institute of Ophthalmology

Moorfields Eye Charity funded 3-Year PhD Studentship. UCL Department / Division. UCL Institute of Ophthalmology. Duration of Studentship. Read more

Supervisors: Prof P Turowski, Prof C Ruhrberg

Open Day(s) 21 April 2023 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Stereospecific Csp3-Csp2 Cross-Coupling of Saturated Heterocyclic Boronates: Application to a Modular Synthetic Platform for the Optimisation of Fragment Hits to 3-D Lead Compounds for Medicinal Chemistry

University of York Department of Chemistry

Background. A long-standing fundamental challenge in cross-coupling chemistry is the formation of stereodefined carbon-carbon bonds using Csp3-Csp2 Suzuki-Miyaura cross-coupling. Read more

Supervisor: Prof P O'Brien

Year round applications PhD Research Project Self-Funded PhD Students Only

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The effects of Interleukin-1 primed mesenchymal stem cells on hypoxic-ischemic brain damage

The University of Manchester Faculty of Biology, Medicine and Health

Hypoxic-ischemic brain damage is one of the main causes of death and neurological disability after stroke worldwide. Read more

Supervisors: Dr E Pinteaux, Prof S Allan

Year round applications PhD Research Project Self-Funded PhD Students Only

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Exploring the acceptability of a diagnostic laparoscopy in women with chronic pelvic pain; a triphasic study.

University of Liverpool Institute of Life Course and Medical Sciences

Background. Chronic pelvic pain (CPP), defined as persistent pain perceived to be originating in pelvic structures and lasting for a period of more than six months, is one of the most common chronic pain problems experienced by women (1). Read more

Supervisors: Dr N Tempest, Dr H Twiddy

10 April 2023 PhD Research Project Competition Funded PhD Project (European/UK Students Only)

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ESRC North West Social Science Doctoral Training Programme (NWSSDTP)

University of Liverpool

This project, joint with HMG's Department for Levelling Up, Housing & Communities (DLUHC), provides a unique and timely opportunity to research a strategic national policy issue. Read more

Funded PhD Programme (Students Worldwide) ESRC Doctoral Training Centre

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Development of high-content fluorescence assays to rapidly monitor CFTR-mediated bicarbonate flow - how do CFTR mutations and modulator drugs affect it?

University College London UCL Division of Biosciences

1) Generation and optimization of a fluorescence probe to monitor CFTR-mediated anion flow. The aim is to create a tool to rapidly quantify CFTR-dependent Cl- and HCO. Read more

Supervisor: Dr P Vergani

Open Day(s) 31 March 2023 PhD Research Project Funded PhD Project (Students Worldwide)

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Is there a Role for Activated Akt in Palatogenesis?

University of Dundee Dental School

Main Aim. The project will use a medial edge epithelial (MEE) cell line as an in vitro model. These cells will be used to investigate the effects of exogenous TGFβ-3 and activation of Akt on cell migration, epithelial to mesenchymal transition (EMT) and apoptosis. Read more

Supervisors: Dr S. J. Jones, Dr M Islam

30 June 2023 PhD Research Project Self-Funded PhD Students Only

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Fragment-Based Lead Generation of Small Molecule Inhibitors of the Nsp3 Macrodomain in SARS-CoV-2

University of York Department of Chemistry

Background. Coronaviruses (CoVs) are important human pathogens and SARS-CoV-2 is responsible for the current COVID-19 pandemic. Read more

Supervisor: Prof P O'Brien

Year round applications PhD Research Project Self-Funded PhD Students Only

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Depositional and diagenetic controls on fluid flow in fractures: Implications for a potential Geological Disposal Facility hosted in the Mercia Mudstone Group, UK

University of Liverpool Department of Earth, Ocean and Ecological Sciences

Objective. The main objective of this PhD project is to develop an understanding of the depositional and diagenetic heterogeneity in the Mercia Mudstone Group and their implications for fluid flow in fracture networks at depth. Read more

Supervisors: Prof R Worden, Prof D Faulkner

17 April 2023 PhD Research Project Funded PhD Project (UK Students Only)

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Unprecedented approach for the synthesis of N-CF3 amides and lactams

University of Warwick Department of Chemistry

A 3.5 year fully-funded PhD position is available in the group of. Dr Mark Greenhalgh. at the University of Warwick. The position will remain open until filled, so if interested please get in touch at your earliest convenience. Read more

Supervisor: Dr M Greenhalgh

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Demystifying the activation mechanism of Glucagon-Like Peptide Receptor 1

Coventry University Centre for Sport, Exercise and Life Sciences

Coventry University (CU) is inviting applications from suitably-qualified graduates for a fully-funded PhD studentship. The glucagon-like peptide receptor (GLP-1R) is a validated target for type 2 diabetes (T2D). Read more

Supervisor: Dr G Deganutti

6 May 2023 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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We have 1,718 1 3 PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

1 3 PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

We have 1,718 1 3 PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

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