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actin PhD Projects, Programmes & Scholarships

We have 19 actin PhD Projects, Programmes & Scholarships

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We have 19 actin PhD Projects, Programmes & Scholarships

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Regulation of nuclear actin in human cancer

Actin is a cytoskeletal protein that plays essential roles in many cellular processes, such as adhesion, intracellular trafficking, membrane dynamics and motility. Read more

THE HARD FACTS ABOUT VASCULAR INFLAMMAGING: Role of vascular stiffness on vascular smooth muscle cell inflammatory phenotype

ABSTRACT. Chronic inflammation is a major factor in the initiation and progression of many cardiovascular pathologies, including atherosclerosis, abdominal aortic aneurysms, and pulmonary artery hypertension. Read more

How does paclitaxel kill cells and why do some cells evade it?

Paclitaxel (Taxol) is a microtubule-stabilizing drug widely used for the treatment of breast, ovarian and lung cancers. For many years, it was thought to kill cancer cells by inducing mitotic arrest, thus preventing proliferation. Read more

Understanding by creating – minimal systems to reveal the underlying mechanisms governing the cell membrane shape and function

  Research Group: Midlands Integrative Biosciences Training Partnership (MIBTP)
The cell plasma membrane is essential for communication between the cell and its environment. It is here that crucial information processing takes place – including steps of signal detection, integration, amplification and transmission. Read more

How do cell identity factors contribute to cytokinesis?

Background. Cytokinesis, the physical division of one cell into two, is fundamental to life and errors can result in abnormal chromosomal numbers, developmental defects, and cancers. Read more
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Significance of cytoskeletal filaments coordination in immunity and cell migration

The cytoskeletal organisation is fundamental for all cellular events, which defines the shape of the cells, the transport of molecules in different cellular domains, and controls the dynamics of cellular function. Read more

Cancer biology: identification of new treatment options for EML4-ALK driven lung cancer through understanding mechanisms of cell division and migration.

Lung cancer is the largest cause of cancer-related deaths in the UK and worldwide. While little progress has been made in long-term survival rates, we now have a good understanding of the genetic drivers raising the prospect of earlier diagnosis and more effective treatments. Read more
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EASTBIO Shaping tissues by pulsed contractions – studying the role of endocytic hubs in actomyosin contractility

  Research Group: Biomedical Sciences Research Centre
BACKGROUND. To shape tissues and organs, cells need to exert forces on their neighbours and respond to them. Individual cells can generate forces with their actin cytoskeleton. Read more

Molecular characterization of Sam68-driven cytoskeletal reorganization

The cytoskeleton is a complex network of various fibres (microtubules, actin, …) that is essential for cells to maintain their shape and internal organization and for their migration. Read more

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