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actin PhD Projects, Programs & Scholarships

We have 18 actin PhD Projects, Programs & Scholarships

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  Defining novel regulators of cancer cell invasion
  Prof M Parsons, Prof J Marshall
Application Deadline: 29 November 2019

Funding Type

PhD Type

The cytoskeleton of cells is known to be essential to the behaviour of cancer cells and their ability to invade throughout the body.
  Actin regulation of nuclear mechanics during DNA repair
  Dr C Toseland
Applications accepted all year round

Funding Type

PhD Type

In eukaryotic cells, the nucleus houses the genomic material and transcription machinery that allows the cell to develop and perform its role.
  Understanding how p18/LAMTOR1 maintains the pulmonary endothelium – a potential therapeutic target for chronic respiratory diseases
  Research Group: Biomedical Research Group
  Dr H Chichger
Applications accepted all year round

Funding Type

PhD Type

Research Group. Biomedical Research Group. https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/biomedical.
  Molecular mechanisms controlling cardiac fibroblast proliferation during cardiac fibrosis
  Dr M Bond
Applications accepted all year round

Funding Type

PhD Type

Applicants are invited for a new self-funded PhD studentship to study the molecular mechanisms of cardiac fibrosis. Myocardial fibrosis is a significant global health problem associated with nearly all forms of heart disease.
  Unraveling the signal regulation network of cell adhesion, migration, and invasion in podosomes and invadopodia
  Dr C Yu
Applications accepted all year round

Funding Type

PhD Type

Integrin-mediated adhesions, such as podosomes and invadopodia, are the biophysical anchor to sense and to translate mechanobiological signals into various cellular events.
  How does the vascular matrix environment influence platelet activation?
  Dr S Calaminus
Application Deadline: 31 March 2020

Funding Type

PhD Type

The platelet is a blood cell that plays a key role in the prevention of bleeding. For platelets to form a clot or thrombus effectively, they must rearrange their actin cytoskeleton to withstand high shear stress from blood flow in the arteries.
  The molecular mechanisms of organelle transport by motor protein myosin-V
  Dr A Hume
Applications accepted all year round

Funding Type

PhD Type

Organelle transport is essential for cellular function and survival, and these processes are disrupted in many common diseases including cancer, diabetes and Alzheimer’s disease.
  Using the fly kidney to develop new treatments for genetic kidney diseases
  Prof A Ong, Dr N Bulgakova
Applications accepted all year round

Funding Type

PhD Type

Polycystic kidney disease is the most common hereditary cause of kidney failure in man. It comprises a spectrum of diseases of which Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common form in adults and Nephronophthisis (NPHP) the most common form in children.
  Exploring the role of the Protein Tyrosine Phosphatase Receptor- Type F (PTPRF) in focal adhesion dynamics
  Dr H Sharpe
Application Deadline: 3 December 2019

Funding Type

PhD Type

The dynamic and reversible phosphorylation of tyrosine residues is a key feature of intercellular communication. Through the regulated activities of kinases and phosphatases, cells are primed to respond to changes in their environment.
  Unveiling the nanomechanical properties of the LINC complex proteins with single molecule resolution
  Prof S Garcia Manyes
Application Deadline: 15 November 2019

Funding Type

PhD Type

Mechanical forces are involved in many physiological processes. While most of the current work in mechanotransduction has focused on the function of focal adhesion proteins and the actin cytoskeleton, the mechanical role of intracellular and nuclear proteins remains rather elusive.
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