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actin PhD Projects, Programs & Scholarships

We have 21 actin PhD Projects, Programs & Scholarships

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  Novel microscopy approaches for investigating relation between the spatio-temporal dynamics of actin filaments and Ca2+ response patterns during T-cell activation
  Dr M Fritzsche, Prof M Dustin
Application Deadline: 11 January 2019
A pivotal event promoting adaptive immune responses is binding of antigens to antigen receptors and subsequent actin cytoskeleton reorganisations resulting in receptor microcluster (MC) formation, intracellular signalling, and ultimately immunological synapse (IS) formation.
  Actin-dependent mechanisms of chromosome segregation in mammalian eggs
  Dr B Mogessie
Applications accepted all year round
Every human life starts when an egg is fertilised by a sperm. Fertilisable eggs are produced from oocytes by a specialised form of cell division called meiosis (1).
  How Chlamydia uses disorder to invade the host cell (BLUMENSCHEINTU19SF)
  Dr T Blumenschein
Application Deadline: 31 May 2019
Intrinsically disordered proteins (IDPs) lack a single well-defined conformation and are instead flexible, exploring multiple possible conformations.
  Investigate a novel, unexplored link between WNT signalling and regulators of cell migration in cancer progression using CRISPR-Cas9 and advanced live cell imaging.
  Dr M Krause
Applications accepted all year round
Cancer is a devastating disease. more than one in three people in the UK will develop cancer in their lifetime. WNT signalling is a key pathway controlling morphogenesis in embryos and it has been shown that perturbations of this pathway promote cancer progression.
  Regulating Cell-to-cell Movement in Plants - Plasmodesmal Gating by a Contractile Cellular Machinery
  Dr P Hemsley, Dr J Tilsner, Dr A Roberts
Application Deadline: 4 January 2019
Background. Plant viruses are major crop pathogens with a global agro-economic impact. The Tilsner lab has recently made major advances in understanding how viruses transport their genome from infected to naïve cells through plasmodesmata, cell-cell-connecting membrane-lined channels.
  Plasmodesmal gating by a contractile cellular machinery
  Research Group: Biomedical Sciences Research Centre
  Dr J Tilsner
Application Deadline: 4 January 2019
Background. Plant viruses are major crop pathogens with a global agro-economic impact. The Tilsner lab has recently made major advances in understanding how they transport their genome from infected into naïve cells through plasmodesmata (PD), cell-cell-connecting membrane-lined channels.
  Molecular mechanisms controlling cardiac fibroblast proliferation during cardiac fibrosis
  Dr M Bond
Applications accepted all year round
Applicants are invited for a new self-funded PhD studentship to study the molecular mechanisms of cardiac fibrosis. Myocardial fibrosis is a significant global health problem associated with nearly all forms of heart disease.
  (BBSRC DTP)Understanding structure and function of the mechanosensors talin and vinculin
  Dr C Ballestrem, Prof C Baldock, Dr A Roseman
Application Deadline: 31 January 2019
Any aberration in the cells’ ability to sense their environment leads to severe health deficiencies including cancer, deficiencies in wound-healing and inflammation.
  The molecular mechanisms of organelle transport by motor protein myosin-V
  Dr A Hume
Applications accepted all year round
Organelle transport is essential for cellular function and survival, and these processes are disrupted in many common diseases including cancer, diabetes and Alzheimer’s disease.
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