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adhesion PhD Projects, Programmes & Scholarships
We have 42 adhesion PhD Projects, Programmes & Scholarships
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Proteomic analyses of adhesion signalling in cancer
Why adhesion? Cell surface adhesion receptors play key roles in the control of cell movement, survival, division and differentiation. Read more
The role of nuclear localisation of adhesion proteins in tumour growth and invasion
Overview. This project seeks to understand how tumour growth and invasion are controlled by the localisation of certain proteins in cancer cells. Read more
The Role of cell adhesion proteins in healthy and cancerous epithelial cells
The cells’ ability to properly communicate with its environment is fundamental for the healthy development of individual organisms. Read more
Regulation of neuronal cell adhesion by a DHHC5/Golga7b palmitoyl-acyltransferase complex.
Palmitoylation (S-acylation), the only known reversible lipid modification of proteins, is an important regulator of protein localisation and function. Read more
Development and characterisation of multifunctional surfaces for durable infection prevention treatments on dental prosthetic device
Applications are invited for a self-funded, 3 year full-time or 6 year part-time PhD project. The PhD will be based in the School of Pharmacy and Biomedical Sciences and will be supervised by Dr Marta Roldo, Professor Gordon Blunn and Dr Mahdi Mutahar. Read more
Investigation into the in-vitro lung deposition of liposomal formulations of the dual fixed-dose combination inhaler
Research Group:
Medicines Development and Pharmaceutical Sciences
Asthma and Chronic Obstructive Pulmonary Disease (COPD) are diseases associated with the airflow in the lungs (WHO, 2013). Inhalation is the most effective route of administration for treating asthma and COPD (Labiris and Dolovich, 2003). Read more
Resorbable antibacterial coatings for orthopaedic implants (NDORMS 2024/15)
Bacterial infections associated with orthopaedic implants are complex to treat and can result in severe complications for patients. Read more
The role of inflammatory cytokines on macrophage cytoskeletal structure and function in diabetes and cardiovasular disease
The Maelor Academic Unit of Medical & Surgical Sciences (MAUMSS) is a novel initiative by the Betsi Cadwaladr University Health Board (BCUHB), and is designed to encourage and support research within the Health Board and to promote academic activity, basic science and clinical research across North Wales (UK) and beyond. Read more
Development of bioactive ultrasound-responsive coatings for the prevention and treatment of orthopaedic implant-related infections
Commercial partner: Adler Ortho®. Implant-related orthopaedic infections pose a very significant burden on patients and healthcare systems globally. Read more
Investigation of antagonism of multiple RGD-binding integrins as a therapeutic strategy in advanced head and neck cancer
Research Group:
Institute of Cancer Therapeutics
Background. The integrins are a family of transmembrane receptors which mediate cell-cell and cell-ECM adhesion, and signalling across the cell membrane involved in pathways controlling cell migration, proliferation, differentiation, cell survival and apoptosis. Read more
Development of carbohydrate-functionalised materials for detection and prevention of medical device-associated infections
Antibiotic-resistant bacteria are a growing problem in the 21st century, causing longer and more serious infections, and resulting in poor outcomes for vulnerable patients. Read more
Develop novel biomimetic antibiofilm surfaces for medical implants
It is estimated that biofilm infections cost about $94 billion p.a. in the United States healthcare system. Read more
MPhil / PhD Studentship in Application of Digital Twin To Wheel / Rail Contact Environment
The project develops application of the Rail Research and Innovation Centre hardware-in-loop facility and specifically the scaled wheel-rail contact rig to research and develop a combined testing and simulation strategy which could be applied for optimising a range of wear, energy use and noise while achieving demanded traction and braking in a range of environments. Read more
Investigate the role of Lamellipodin and the NHS protein family, key regulators of the actin cytoskeleton, in cancer cell migration using CRISPR-Cas9, microfluidics, and advanced live cell imaging.
Cancer is a devastating disease. more than one in three people in the UK will develop cancer in their lifetime. Metastasis is the primary cause of cancer related deaths. Read more
Investigate the molecular mechanism controlling FEME (Fast Endophilin Mediated Endocytosis) in directed cancer cell migration using CRISPR, biochemistry, and advanced microscopy methods.
Cancer is a devastating disease. more than one in three people in the UK will develop cancer in their lifetime. Metastasis is the primary cause of cancer related deaths. Read more
