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aim PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

We have 1,388 aim PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

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Investigation of Appropriate Models and Design Strategies for TB household contact studies

Aim 1. To develop a random directed graph model (RDM) suitable for tuberculosis household contact studies. RDM should be adapted to incorporate key epidemiological features of TB, specifically long latency and the fact that only TB cases are infectious. Read more

Zoonotic Pathogen Growth Rate – A Marker for Environmental Mapping of Disease Virulence and Therapy Resistance

The Challenge. Fasciola hepatica is a zoonotic pathogen that causes fasciolosis in animals and humans. Control is precarious and in the absence of an effective vaccine reliant on a small portfolio of flukicides to which resistance is growing. Read more

Antimicrobial resistance dynamics and antimicrobial use in wildlife rehabilitation facilities in the United Kingdom

Supervisors. Dr Fernando Sanchez-Vizcaino Buendia (primary supervisor), Dr Irene Bueno. Background. Antimicrobial resistance (AMR) is one of the greatest global public health threats of the 21st century (Prestinaci et al. Read more

Design of novel inhibitors of AIM-2 for the treatment of inflammation.

Inflammation is a contributing factor in a range of therapeutic areas including stroke, Alzheimer’s disease and cancer. A cause of Inflammation is through the activation of multi-protein complexes called inflammasomes, which facilitates the release of cytokines, including IL-1b. Read more
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What is the mechanistic link between mitochondrial dysfunction and protein aggregation; a biochemistry and imaging study

Background. Mitochondrial dysfunction is a key pathogenic mechanism in multiple neurodegenerative diseases, including Parkinson’s Disease; with evidence from both sporadic and familial patient groups and multiple animal models. Read more

How GABA neurones in the DVC control glucose metabolism

The Dorsal Vagal Complex (DVC) of the brain is an important regulator of glucose metabolism and food intake. The Nucleus of the Solitary Tract (NTS) in the DVC senses insulin and triggers a neuronal relay to decrease hepatic glucose production (HPG) in rodents. Read more

Fatigue behavior of architectured materials obtained by additive manufacturing

Option 1. EFFECT OF CELL MORPHOLOGY AND MICROSTRUCTURE ON THE MECHANICAL BEHAVIOUR OF ARCHITECTURED MATERIALS. The development of new additive manufacturing processes has changed the way we consider process/microstructure/properties relationships of materials. Read more

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