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We have 21 als PhD Projects, Programmes & Scholarships

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als PhD Projects, Programmes & Scholarships

We have 21 als PhD Projects, Programmes & Scholarships

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MRC DiMeN Doctoral Training Partnership: Developing novel gene therapy approaches to inhibit the unconventional translation of neurotoxic dipeptide-repeat proteins in pre-clinical models of C9ORF72-ALS/FTD

University of Sheffield MRC DiMeN Doctoral Training Partnership
Background. Hexanucleotide repeat expansions in C9orf72 are the most common causes of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), a spectrum of fatal neurodegenerative diseases leading to progressive paralysis and altered personality features respectively. Read more
 Supervisors: Prof G Hautbergue, Prof M Azzouz
 17 December 2023  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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MRC DiMeN Doctoral Training Partnership: Functional biomechanical assessment of treatment efficacy in Amyotrophic lateral sclerosis

University of Sheffield MRC DiMeN Doctoral Training Partnership
Amyotrophic lateral sclerosis (ALS) is a major subtype of Motor Neurone Disease (MND). This is a progressive neurodegenerative condition which affects upper and lower motor neurons, resulting in impaired muscle function which can cause muscle weakness which can impact a variety of body systems. Read more
 Supervisors: Prof C McDermott, Dr T Bonci, Prof C Brocket, Dr E Buckley
 17 December 2023  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Comparative proteostasis capacity of progenitors and neurons in hiPSC motor neuron disease models

Babraham Institute (Cambridge) Babraham Research Campus
Academic Supervisor. Ian McGough. Co-Academic Supervisor. Teresa Rayon. Industrial Partner. Axol Bioscience. Read more
 Supervisor: Dr IM McGough
 1 December 2023  PhD Research Project  Funded PhD Project (Students Worldwide)
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EMC-2024-3_McGurk: Elucidating how the poly(ADP-ribose) polymerases control the progression of motor neuron disease.

University of Edinburgh Centre for Clinical Brain Sciences
THIS PROJECT WILL BE BASED AT THE UNIVERSITY OF DUNDEE. This project is on offer as part of the studentship scheme of the Euan MacDonald Centre for Motor Neuron Disease Research. Read more
 Supervisors: Dr L McGurk, Dr G Findlay
 19 January 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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EMC-2024-1_Allodi: Investigating the role of Munc 13-1 in Amyotrophic lateral sclerosis

University of Edinburgh Centre for Clinical Brain Sciences
THIS PROJECT WILL BE BASED AT THE UNIVERSITY OF ST ANDREWS. This project is on offer as part of the studentship scheme of the Euan MacDonald Centre for Motor Neuron Disease Research. Read more
 Supervisors: Dr I Allodi, Dr C Imig
 19 January 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Development of mechanism-based therapeutics for Amyotrophic Lateral Sclerosis (ALS)

Ben-Gurion University of the Negev Department of Clinical Biochemistry and Pharmacology
The laboratory of Prof. Read more
 Supervisor: Prof SE Engel
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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EMC-2024-5_Sibley: Investigating the role of TDP-43 mis-splicing events in MND pathogenesis

University of Edinburgh Centre for Clinical Brain Sciences
This project is on offer as part of the studentship scheme of the Euan MacDonald Centre for Motor Neuron Disease Research. The Euan MacDonald Centre is a multi-disciplinary network of MND researchers across Scotland. Read more
 Supervisors: Dr C Sibley, Dr M Horrocks
 19 January 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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EMC-2024-6_Sleeman: Analysis of the roles of protein arginine methylation in motor neuron disease using quantitative proteomics

University of Edinburgh Centre for Clinical Brain Sciences
THIS PROJECT WILL BE BASED AT THE UNIVERSITY OF ST ANDREWS. This project is on offer as part of the studentship scheme of the Euan MacDonald Centre for Motor Neuron Disease Research. Read more
 Supervisors: Dr J Sleeman, Dr SS Shirran
 19 January 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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EMC-2024-4_Murray: Investigating Strategies to Promote Axon Regeneration in Motor Neuron Disease

University of Edinburgh Centre for Clinical Brain Sciences
This project is on offer as part of the studentship scheme of the Euan MacDonald Centre for Motor Neuron Disease Research. The Euan MacDonald Centre is a multi-disciplinary network of MND researchers across Scotland. Read more
 Supervisor: Dr L Murray
 19 January 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Understanding the role that RNA helicase UPF1 plays in nuclear processes of gene expression

University of Birmingham School of Biosciences
Accurate gene expression is crucial for the survival of all life forms. RNA helicases are a large class of enzymes involved at the multiple stages of the process, including transcription, pre-mRNA processing and translation. Read more
 Supervisor: Dr S Brogna
 4 January 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Investigating immune contributions to frontotemporal dementia and motor neuron disease

The University of Manchester Faculty of Biology, Medicine and Health
Frontotemporal dementia (FTD) is the 2nd most common form of dementia affecting younger people, with a typical age of onset in the mid-late 50s. Read more
 Supervisors: Dr SR Ryan, Prof D Brough
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Exploring Sensorimotor Function and Developing Rehabilitation Strategies using Experimental and Computational Approaches

University of Leeds Faculty of Biological Sciences
In collaboration with a multidisciplinary team consisting of biologists, clinicians, engineers, mathematicians, and computational biologists and startups around the globe, we aim to decipher the organizational principles of sensorimotor function in mammals. Read more
 Supervisor: Dr S Chakrabarty
 Open Day(s)  Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Targeting ageing and neurodegenerative diseases using the fruit-fly Drosophila melanogaster

Royal Holloway, University of London School of Biological Sciences
In the last 20 years the fruit fly Drosophila melanogaster emerged as a pre-eminent model system for studying changes that occur during both normal and pathological ageing (~75 per cent of the genes that cause disease in humans are also found in the fruit fly!). Read more
 Supervisor: Dr H Augustin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Protein misfolding and aggregation in biomolecular condensates

Ruhr-University Bochum Ruhr-University Bochum
Protein misfolding and aggregation in biomolecular condensates. We offer a 3 year PhD position that is jointly financed and supervised by Prof. Read more
 Supervisor: Prof S Ebbinghaus
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Understanding the 21st Century Digital Charitable Donor (Ref: RDF24/BL/MOS/HART)

Northumbria University Faculty of Business and Law
There is ample evidence in the charitable sector that online channels are increasingly utilised by donors (CAF, 2022). Whilst evident pre-pandemic, this was accelerated rapidly through lockdowns which removed opportunities for cash-based giving. Read more
 Supervisors: Dr D Hart, Dr S Gonul
 26 January 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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