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als PhD Projects, Programmes & Scholarships
We have 11 als PhD Projects, Programmes & Scholarships
Enhancing stem cell-derived motor neuron function as a therapeutic approach in Amyotrophic Lateral Sclerosis. MRC GW4 BioMed DTP PhD studentship 2025/26
Project Summary. Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, for which there is currently no effective treatment. Read more
Deciphering novel ALS signalling pathways: Biomarker discovery and developing therapeutic strategies
Motor neuron disease also referred as Amyotrophic lateral sclerosis (ALS) is a rapidly progressive debilitating disease affecting upper and lower motor neurons with a median survival rate of 2-3 years. Read more
Unveiling Early Motor Neurone Disease Biomarkers: Insights from Neuromuscular Junction Dynamics
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease that leads to the degeneration of motor neurons (MNs) in the brain and spinal cord. Read more
Using single-cell nanopore long-read sequencing to identify drivers of neurodegenerative disorders
Are you passionate about using cutting-edge computational approaches to tackle complex neurological disorders? Join our dynamic research team at Garvan Institute of Medical Research in Sydney as we embark on an exciting journey to understand Amyotrophic Lateral Sclerosis (ALS) at unprecedented resolution. Read more
High-resolution imaging of the human neuromuscular junction
The neuromuscular junction (NMJ) is the final synapse linking the nervous system to skeletal muscle, critical for all movements of the body. Read more
PhD (f/m/x) Position on Memory and Spatial Coding in Superagers
DZNE is a world-leading, internationally oriented center for cutting-edge research into diseases of the nervous system. With its outstanding research personalities and state-of-the-art infrastructure, it offers the best conditions for publications and results at the highest level. Read more
How do atypical E3 ligases facilitate their biology?
The covalent attachment of the small protein ubiquitin to substrates regulates virtually all cellular processes and its modulation with small molecules is set to revolutionise modern medicine. Read more
Identification of Novel Mechanisms Supporting Axon Survival and Investigation of their Therapeutic Potential
Programmed axon death is a widespread and completely preventable mechanism in injury and disease (Coleman and Hoke, Nat Rev Neurosci, 2020). Read more
Molecular dynamics of intrinsically disordered proteins in health and disease
Proteins are long polymer chains consisting of twenty different amino-acids. Their sequence determines in what ordered structures the proteins fold. Read more
Targeting human neurodegenerative diseases using the fruit-fly Drosophila melanogaster
Almost a million of people in the UK suffer from neurodegenerative disorders. Alzheimer’s disease, dementia with Lewy bodies, and Frontotemporal dementia are the most common causes of neurodegenerative dementias. Read more
Cardiovascular and Neuromuscular Functions around the Clock: Harnessing Protective Endogenous Mechanisms towards Smarter Design of Novel Therapies and Interventions
Optimal tissue and organ is essential for long-term health and quality of life. One such important regulator within the body is related to circadian rhythms, which control ~24h cycles in many physiological processes such as sleep/wake cycles, physical activity/rest cycles, drug metabolism and hormones. Read more
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