alzheimer PhD Projects, Programs & Scholarships

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Several risk factors for Alzheimer’s disease including diabetes and midlife obesity are age-dependent and have an obvious metabolic component resulting in impaired glucose metabolism.

Ca2+ signalling in neurodegeneration and Alzheimer’s disease

University of Leeds
Faculty of Biological Sciences

Research Group: School of Biology

Prof I A Hope

Applications accepted all year round

Funding Type

PhD Type

Competition Funded PhD Project (European/UK Students Only)

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities.

Human variants of the ryanodine receptor, the main intracellular calcium ion channel, could be responsible for Alzheimer’s disease.

Investigating the links between osteoporosis & Alzheimer’s disease – effects of β-amyloid upon the mechanical set-point in bone

Queen Mary University of London
Institute of Dentistry

Dr S McArthur, Dr SCF Rawlinson

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Background. Individuals with Alzheimer’s disease are more likely to suffer from osteoporosis (the loss of bone mass and strength) than age-matched individuals; significantly contributing to the frailty associated with dementia.

Determining brain glycosylation in ageing and Alzheimer’s disease

University of Bradford
Faculty of Life Sciences

Research Group: Pharmacology and Experimental Therapeutics

Dr R Williamson, Dr C Sutton

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Increasing age is associated with lower levels of cognitive performance; concomitant with this is a decrease in brain glucose metabolism.

ERK5 MAPK signalling in Alzheimer’s disease

University of Bradford
Faculty of Life Sciences

Research Group: Pharmacology and Experimental Therapeutics

Dr J Muller, Dr S Kantamneni

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Neurodegenerative diseases have devastating effects on individuals’ lives and our society, with no effective treatments available.

Protein Misfolding and the Molecular Basis of Alzheimer’s Disease

Queen Mary University of London
School of Biological & Chemical Sciences

Dr J Viles

Applications accepted all year round

Funding Type

PhD Type

Awaiting Funding Decision/Possible External Funding

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This supervisor does not yet know if funding is available for this project, or they intend to apply for external funding once a suitable candidate is selected. Applications are welcome - please see project details for further information.

Background. World-wide one in three people over the age of 65 will die with Alzheimer’s Disease (AD). The disease is characterised by deposits of amyloid plaques and fibrils of amyloid-beta peptide (Ab) are their main constituent.

Characterisation of the neuronal receptor for soluble amyloid precursor protein: a route to new therapeutic targets for Alzheimer’s disease

The University of Manchester
Faculty of Biology, Medicine and Health

Prof N Hooper, Prof M J Humphries

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Alzheimer’s disease (AD) is the commonest form of dementia for which currently there is no means of stopping or even slowing the disease.

Investigating the link between amyloid-β oligomers, neuroinflammation and cognitive deficits in preclinical models for Alzheimer’s Disease

The University of Manchester
Faculty of Biology, Medicine and Health

Dr M Harte, Prof J Neill

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Currently four out of the five pharmacological treatments used for Alzheimer’s disease (AD) are acetylcholinesterase inhibitors aimed at boosting the amount of acetylcholine in the brain, with the fifth being an N-methyl-D-aspartate (NMDA) receptor antagonist.

Neurological reserve as a pivotal mechanism for psychiatric symptoms in Alzheimer’s disease

University of Sheffield
Department of Neuroscience

Prof A Venneri, Dr M De Marco

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Patients with Alzheimer’s disease (AD) may experience and show a whole range of clinical symptoms. Of these, psychiatric symptoms such as apathy, depression and anxiety play a major role in that they are highly debilitating for patients and carers.

The impact of zinc deficiency on Alzheimer’s disease

The University of Manchester
Faculty of Biology, Medicine and Health

Dr C Lawrence, Prof D Brough

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

In addition to memory problems, people with Alzheimer’s disease (AD) also experience ‘non-memory’ behavioural symptoms including depression, anxiety, and agitation.

TRPM2 channel mechanism of neuroinflammation and neurodegeneration in Alzheimer’s disease

University of Leeds
Faculty of Biological Sciences

Research Group: School of Biomedical Sciences

Dr L H Jiang, Dr I Wood

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Alzheimer’s disease (AD) is the most common cause of dementia and also a major cause of morbidity and mortality. Currently, there is no effective therapeutics to treat or slow the disease progress.

Screening of chemical libraries using iPS models for investigating the role of prion protein in Alzheimer’s disease

University of Sheffield
Department of Chemistry

Prof B Chen

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Background. AD has been identified as a protein misfolding disease (proteopathy). The disease is caused by accumulation of two major amyloids.

AI and Machine Learning for the diagnosis and monitoring of Parkinson’s and Alzheimer’s disease

University of York
Department of Electronic Engineering

Research Group: Intelligent Systems and Nanoscience

Prof S Smith

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

The Department has long-standing research collaborations with hospitals and medical centres worldwide developing new approaches to the diagnosis and monitoring of neurological conditions, including Parkinson’s and Alzheimer’s.

Tackling neurovascular dysfunction in dementia: a cell biology and biomaterials approach

The University of Manchester
Faculty of Biology, Medicine and Health

Prof N Hooper, Dr M Domingos, Dr T Wang

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Neurovascular dysfunction is a central process in the pathogenesis of Alzheimer’s disease and other dementias. In the brain, vascular and neuronal structures are tightly integrated forming the multicellular neurovascular unit comprising endothelial cells, pericytes, astrocytes, microglia and neurons.

Investigating glial cell dysfunction in neurodegenerative diseases

University of Nottingham
School of Life Sciences

Dr G Sheridan

Applications accepted all year round

Funding Type

PhD Type

PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.

This project does not have funding attached. You will need to have your own means of paying fees and living costs and / or seek separate funding from student finance, charities or trusts.

Neurodegenerative disorders, such as Alzheimer’s disease, are often associated with chronic neuroinflammation and glial cell dysfunction that acts to exacerbate neuronal damage and loss of synapses.