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amyloid PhD Projects, Programs & Scholarships

We have 24 amyloid PhD Projects, Programs & Scholarships

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  The molecular basis of a genetic susceptibility gene in Alzheimer’s disease: the case of cystatin C
  Dr R Staniforth
Applications accepted all year round

Funding Type

PhD Type

Degenerative diseases associated with ageing occur sporadically and are associated with the misfolding and aggregation of a number of proteins in vivo.
  Investigating phenotypic, proteomic and functional changes in microglia in a preclinical model for sporadic Alzheimer’s disease research (Manchester-Melbourne Dual Award)
  Dr M Harte, Dr A Tirella
Application Deadline: 31 January 2020

Funding Type

PhD Type

Current treatments for Alzheimer’s disease (AD) are symptomatic and do little to slow down the progression of the disease. This has led to an array of research investigating hallmark pathologies in the search for novel therapeutic strategies.
  Ca2+ signalling in neurodegeneration and Alzheimer’s disease
  Research Group: School of Biology
  Prof I A Hope
Applications accepted all year round

Funding Type

PhD Type

Human variants of the ryanodine receptor, the main intracellular calcium ion channel, could be responsible for Alzheimer’s disease.
  Roles of post-translational modifications in neurodegenerative protein aggregation
  Dr F Aprile
Application Deadline: 29 February 2020

Funding Type

PhD Type

A fully funded PhD studentship position is available in the Aprile group in the Department of Chemistry at the White City Campus of Imperial College London.
  Are Tau fibrils induced by phosphorylation and the interaction with 14-3-3 proteins relevant for Alzheimer disease?
  Dr J Hritz, Dr JN Nováček, Dr J Pribyl
Application Deadline: 20 February 2020

Funding Type

PhD Type

Several neurodegenerative diseases are associated with the formation of fibrous protein aggregates. The fibrillization of amyloid beta peptide into amyloid plaques and the agregation of hyperphosphorylated tau protein into neurofibrillar tangles are main neuropatological signs of Alzheimer disease.
  Investigating the molecular mechanisms and consequences of ANP aggregation for cardiovascular disease; a computational and experimental approach
  Dr J Madine, Dr D J Rigden, Dr M Winn
Applications accepted all year round

Funding Type

PhD Type

Atrial natriuretic peptide (ANP) is a cardiovascular hormone synthesised and secreted by myocytes in the atrial wall where it regulates atrial blood volume and vasodilation.
  Role of phosphorylated 14-3-3 proteins
  Dr J Hritz, Assoc Prof V Bryja
Application Deadline: 1 February 2020

Funding Type

PhD Type

14-3-3 proteins play key role in the neurobiochemistry of brain and are also associated with neurodegenerative amyloid diseases such as Alzheimer and Parkinson disease.
  (BBSRC DTP) Selective knockdown of proinflammatory microRNAs to tackle neurodegeneration and cognitive decline: myth or reality?
  Dr E Bichenkova, Prof J Neill, Dr F Roncaroli, Prof D Clarke
Application Deadline: 31 January 2020

Funding Type

PhD Type

Neurodegenerative diseases (e.g. multiple and amyotrophic lateral sclerosis, Alzheimer’s and Parkinson’s diseases) have tremendous psychological, clinical and social impact, which becomes increasingly challenging in the global trend of population aging.
  Analysing the factors that regulate expression of blood-brain barrier drug transporter proteins
  Dr J L Penny, Dr C Demonacos
Applications accepted all year round

Funding Type

PhD Type

In order to treat diseases associated with the central nervous system (CNS), e.g. cancer, Parkinson’s disease, depression, it is essential for therapeutic drugs to be able to penetrate into the brain.
  Understanding cellular and network mechanisms underlying memory dysfunction in Alzheimer’s disease
  Research Group: Centre for Clinical Brain Sciences
  Dr S Wang, Prof S Grant
Application Deadline: 29 February 2020

Funding Type

PhD Type

Memory impairment is among the early signs in Alzheimer’s disease (AD) that significantly affects daily function. It is vital to understand how neurons encoding memory (i.e.
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