An integrated approach to the study of cellular interactions with amyloid
Astbury Centre for Structural Molecular Biology
Dr E W Hewitt, Prof S E Radford
Applications accepted all year round
The formation of insoluble amyloid fibrils is associated with a spectrum of human disorders, the amyloidoses, which include Alzheimer’s, Parkinson’s, type 2 diabetes and dialysis related amyloidosis (DRA).
Inhibiting protein-protein interactions in the early stages of amyloid formation
BBSRC White Rose DTP
Prof F. Sobott, Prof S E Radford
7 February 2019
Amyloidosis is a pathological condition associated with the aggregation of proteins into fibrils. Despite the importance of amyloid diseases in today’s society, therapies remain remote, due to a lack of understanding of some of the fundamental molecular processes involved.