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We have 15 amyotrophic PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
amyotrophic PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
We have 15 amyotrophic PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
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Investigating the oligogenic model of Amyotrophic Lateral Sclerosis (ALS; motor neuron disease, MND)
Research Group:
Neuroscience
Applications are invited for a multidisciplinary PhD studentship funded by the Motor Neurone Disease Association to study the cumulative contribution of coinherited subthreshold amyotrophic lateral sclerosis (ALS) risk gene variants in the development of cellular hallmarks of ALS pathology. Read more
Development of mechanism-based therapeutics for Amyotrophic Lateral Sclerosis (ALS)
The laboratory of Prof. Stanislav Engel (. https://engels45.wixsite.com/engelslab. Read more
Last chance to apply
Identification of gene-environment interactions that enable individualised risk prediction in ALS patients
At least 90% of amyotrophic lateral sclerosis (ALS) cases are classified as sporadic, where there is no family history supporting transmission of a disease-causing genetic mutation. Read more
The cellular response to stress: roles in disease and ageing
All living organisms need to adapt to their environment in order to survive and reproduce. They are subjected to many stresses including altered oxygen levels, heat or cold, irradiation, infection and injury. Read more
Fully funded PhD studentship opportunities in the Neuroscience Institute at the University of Sheffield
The Neuroscience Institute brings together leading experts in medicine, science and engineering to better understand the nervous system and tackle the biggest challenges in neuroscience. Read more
Last chance to apply
Cross-talk between axon maintenance and DNA damage in neurodegeneration
Join a team of experts to investigate the molecular mechanisms that underlie neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, and Amyotrophic Lateral Sclerosis. Read more
Last chance to apply
The role of post-translational protein modifications (PTMs) in the regulation of RNP biomolecular condensates in health and motor neuron disease
Background. Eukaryotic cells contain a whole repertoire of microscopically visible, non-membrane-bound RNA-protein complexes - biomolecular condensates that are maintained through a combination of protein-protein, protein-RNA and RNA-RNA interactions. Read more
Last chance to apply
Regulation of dense-core vesicle function and its role in dementia
Applications are invited for a fully funded PhD studentship in the laboratories of Prof Kurt De Vos (. http://sitran.org/people/devos/). Read more
Last chance to apply
Developing a genomic biomarker for the early detection of Neurodegeneration. Exeter Biomedical Research Centre - NIHR funded PhD Studentship for 2023/24 Entry,
About the Partnership. The National Institute for Health Research Biomedical Research Centre for Exeter (NIHR Exeter BRC) is a collaboration between University of Exeter (UoE), The Royal Devon University Healthcare NHS Foundation Trust (NHS Royal Devon) and other SW NHS organisations. Read more
Vision-based AI for automatic detection of individual and social behaviour in Rodents
Rodents are the most extensively used models to understand the cellular and molecular underpinnings of behaviour, neurodegenerative and psychiatric disorders, as well as, for the development of interventions and pharmacological treatments. Read more
Investigating the role of SOD1 in sporadic Motor Neuron Disease patients using structural proteomics
Background. Motor Neuron Disease/Amyotrophic lateral sclerosis (ALS) is a complex neurological disorder characterised by the progressive degeneration of motor neurons that is thought to be caused by mitochondrial dysfunction leading to oxidative stress and neuroinflammation. Read more
Decoding Speech using Invasive Brain-Computer Interfaces
For individuals who have impaired speech or complete loss of speech as a result of neurodegenerative diseases such as motor neurone disease (MND) or amyotrophic lateral sclerosis (ALS), there is an urgent need to develop revolutionary technologies using the latest advances in automatic speech recognition (ASR) and brain signal processing (BSP). Read more
Applied optogenetics to study the influence of neuronal activity on neurodegeneration
Optogenetic approaches use genetically encoded, light-inducible proteins that can be expressed in specific tissues and cell types (e.g. Read more
Neurodegenerative disorders
We are currently looking for a PhD candidate to work on the following projects. Understanding enzymes linked to neurodegeneration and antiviral defence. Read more
Synaptic dysfunction in Drosophila models of neurodegenerative diseases
Almost a million of people in the UK suffer from neurodegenerative disorders. Alzheimer’s disease (AD), dementia with Lewy bodies (DLB), and frontotemporal dementia (FTD) are the most common causes of neurodegenerative dementias. Read more
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