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We have 9 amyotrophic lateral sclerosis PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
amyotrophic lateral sclerosis PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
We have 9 amyotrophic lateral sclerosis PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
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Development of mechanism-based therapeutics for Amyotrophic Lateral Sclerosis (ALS)
The laboratory of Prof. Stanislav Engel (. https://engels45.wixsite.com/engelslab. Read more
Decoding Speech using Invasive Brain-Computer Interfaces
For individuals who have impaired speech or complete loss of speech as a result of neurodegenerative diseases such as motor neurone disease (MND) or amyotrophic lateral sclerosis (ALS), there is an urgent need to develop revolutionary technologies using the latest advances in automatic speech recognition (ASR) and brain signal processing (BSP). Read more
Long non-coding RNA NEAT1 isoforms in the regulation of cellular glucose metabolism downstream TDP-43 dysfunction in ALS
Amyotrophic lateral sclerosis (ALS) is a debilitating neurodegenerative disease caused by motor neuron loss that currently has no cure or a disease-modifying treatment. Read more
Targeting ageing and neurodegenerative diseases using the fruit-fly Drosophila melanogaster
In the last 20 years the fruit fly Drosophila melanogaster emerged as a pre-eminent model system for studying changes that occur during both normal and pathological ageing (~75 per cent of the genes that cause disease in humans are also found in the fruit fly!). Read more
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Ion mobility mass spectrometry investigations into the conformations and complexes of ubiquitin shuttle proteins
Summary. During this PhD project you will use ion mobility mass spectrometry to investigate the conformations of ubiquitin (Ub) shuttle proteins. Read more
The cellular response to stress: roles in disease and ageing
All living organisms need to adapt to their environment in order to survive and reproduce. They are subjected to many stresses including altered oxygen levels, heat or cold, irradiation, infection and injury. Read more
Investigating the role of SOD1 in sporadic Motor Neuron Disease patients using structural proteomics
Background. Motor Neuron Disease/Amyotrophic lateral sclerosis (ALS) is a complex neurological disorder characterised by the progressive degeneration of motor neurons that is thought to be caused by mitochondrial dysfunction leading to oxidative stress and neuroinflammation. Read more
Applied optogenetics to study the influence of neuronal activity on neurodegeneration
Optogenetic approaches use genetically encoded, light-inducible proteins that can be expressed in specific tissues and cell types (e.g. Read more
Neurodegenerative disorders
We are currently looking for a PhD candidate to work on the following projects. Understanding enzymes linked to neurodegeneration and antiviral defence. Read more
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