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angiogenesis PhD Projects, Programmes & Scholarships
We have 16 angiogenesis PhD Projects, Programmes & Scholarships
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Local protein synthesis in angiogenesis
This proposal aims to investigate how localised mRNA translation within endothelial cells regulates blood vessel formation. Angiogenesis, or the emergence of new blood vessels, is a complex biological process that involves the coordinated migration of endothelial cells. Read more
Cytoskeletal dynamics and intracellular trafficking in angiogenesis
Angiogenesis is the fundamental physiological process by which new blood vessels are generated from pre-existing vasculature. Read more
Transcriptional control of vascular development
Sprouting of new capillaries from pre-existing vessels (angiogenesis) promotes the formation of almost all blood vessels during development, growth and tissue regeneration. Read more
Lasers and Light Source guided Osteogenesis and Angiogenesis for Tissue Engineering
Research Group:
School of Chemical and Process Engineering
The project will investigate the growth of osteoblast and endothelial cells in in vitro model on a given bone scaffold and investigate the light-induced cell induction and conduction for osteogenesis and angiogenesis. Read more
TARGETING DNA METHYLATION AS A NOVEL APPROACH TO RESTORE ENDOTHELIAL COLONY-FORMING CELL ANGIOGENIC DYSFUNCTION IN ISCHAEMIC DISEASE
The overall aim of this project is to investigate whether epigenetic regulation, specifically DNA methylation, plays a critical role in promoting endothelial colony-forming cell (ECFC) dysfunction, which may be targeted to promote therapeutic angiogenesis for improved management of cardiovascular disease (CVD). . Read more
Using zebrafish models to investigate cerebral arteriovenous malformations
Cerebral Arteriovenous Malformations (cAVM) relate to a spectrum of conditions associated with blood vessel abnormalities of the brain [1]. Read more
Anticancer potentials of isothiocyanates, diterpenoids, and their molecular mechanisms of interactions (BAOY_U22CPRTFMH)
High consumption of cruciferous vegetables can reduce the risk of cancer. Read more
Inorganic chaperones fused to fungal derived chemotherapeutic agents for the treatment of neuroblastoma
This is a unique and cutting-edge PhD research opportunity in the multidisciplinary field of nanotechnology for a student with a strong background in chemistry / biochemistry interested in applying knowledge and developing drugs and drug delivery systems for cancer chemotherapy. Read more
Modulating endothelial cell crosstalk within tissues to delay and/or reverse ageing
Blood vessels, running across all tissues, provide a unique biological hub that integrates ageing signals at the molecular, cellular, and organ levels. Read more
Regulation of blood vessel formation with therapeutic purposes in cancer and cardiovascular disease
Cancer and cardiovascular disease are currently the two most common causes of mortality and morbidity worldwide. Read more
Design, synthesis and evaluation of protease-activated anti-cancer prodrugs
Research Group:
Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more
Redefining the use of steroids in endometriosis: key mechanisms and new solutions
Endometriosis is a debilitating condition that affects an estimated 190 million women of reproductive-age worldwide [1]. In endometriosis, cells similar to the lining of the uterus typically form lesions around the bowel, ovaries and bladder, causing chronic inflammation and scarring. Read more
Evolution of vertebrate blood vessels
The blood vessels are the core elements of the circulatory system of animals, and their malfunction is related to most human diseases including cancer and heart attacks. Read more
Smoking and psoriasis: does smoking augment the angiogenic drive to the development of psoriasis and does smoking cessation have utility for psoriasis management?
Vascular endothelial growth factor A (VEGF-A)-mediated angiogenesis plays a key role in the pathogenesis of psoriasis; a common, inflammatory disease associated with significant extracutaneous morbidity and psychological distress. Thus, patients with psoriasis live with a complex multi-system disease which be a barrier to healthy lifestyle choices. . Read more
Inter- and intra-cellular signalling in the development of fibrosis in the hypertensive heart
Project Overview. Heart failure is a leading cause of morbidity and mortality worldwide. In terms of volume, the normal heart is composed mostly of terminally-differentiated contractile cells (cardiomyocytes), responsible for the pump action of the heart. Read more
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