Immune mediated inflammatory diseases (IMIDs) including Rheumatoid arthritis (RA), inflammatory bowel disease and Sjogren’s syndrome result from interactions between innate and adaptive immune cells with stromal fibroblasts driving both inflammation and tissue damage.
Wellcome Trust 4-year Doctoral Programme in Ion Channels and Membrane Transport in Health and Disease (OXION). OXION is an Oxford-based consortium of world-leading scientists with a general interest in the role of ion channels and membrane transport in health and disease.
Background. Defects in spatial genome organisation have recently been linked to human disease and the National Institutes of Health, USA director speculated that most as yet unidentified disease alleles will occur in non-coding genome regions.