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We have 32 antibiotic resistance PhD Projects, Programmes & Scholarships

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antibiotic resistance PhD Projects, Programmes & Scholarships

We have 32 antibiotic resistance PhD Projects, Programmes & Scholarships

How do interactions in the microbiome shape the evolution of antibiotic resistance in bacterial pathogens?

Antibiotic resistance in pathogenic bacteria poses a fundamental threat to human health. It is estimated that antibiotic resistant infections are already directly responsible for at least one million deaths per annum and this number is predicted to rise dramatically by 2050. Read more

Modification of antibiotics to improve efficacy / safety

With increasing concern over antibiotic resistance, antibacterial agents such as chloramphenicol and colistin, which have frequently been passed over in the past because of concerns over toxicity, are now becoming more important to tackle resistant bacterial strains. . Read more

Clinical Gastroenterology: Investigation of Fidaxomicin Resistance Mechanisms in Clostridium difficile

Clostridium difficile is a leading pathogen in healthcare-associated diarrheal infections. C. difficile has a plastic genome with multiple mobile genetic elements and recognized capacity to acquire genes involved in resistance and virulence. Read more

Deconstructing biofilms

  Research Group: Physics of Life
Colonies of bacteria form biofilms to protect themselves from outside threats, like antibiotics, by making an extracellular matrix. Read more

Novel strategy for treatment of chronic wounds via multi-functional liposomal nanocarriers

  Research Group: Medicines Development and Pharmaceutical Sciences
A confounding issue of non-healing skin wounds is the presence of pathogenic bacteria, that protect themselves from conventional antibiotic treatments by encasing themselves within protective shields (biofilms). Read more

Optimizing phage-antibiotic-synergies to kill bacterial pathogens

Phage therapy, the use of viruses that only infect bacterial cells and kill them, is a promising potential solution to the antimicrobial resistance crisis that is threatening modern medicine1. Read more

Novel design and formulation strategies to enhance drug delivery

The main research activities of my research group concern the improvement of traditional drug formulation and development of novel drug and formulation strategies to enhance bioavailability and patient acceptability. Read more

Self-funded PhD- Understanding the molecular mechanism of a bacterial genome defence system and its synergy with CRISPR-Cas

Prokaryotes have evolved over billions of years alongside their viruses, the bacteriophages, or “phages”. To prevent viral infection, prokaryotes have evolved rudimentary immune mechanisms, the most widespread and well-studied of which are the Restriction-Modification and the CRISPR-Cas enzymes. Read more

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