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We have 35 antibodies PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
antibodies PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
We have 35 antibodies PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
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The clinical significance of antibodies to transglutaminase 6 in gluten sensitivity
Background. Anti-transglutaminase 6 antibodies (anti- TG6) have been described and studied by our group in collaboration with Professor Aeschlimann at Cardiff University. Read more
Chemical glycoengineering of therapeutic antibodies
Glycosylation is the most common posttranslational protein modification. Recombinant therapeutic glycoproteins (RTGs) such as monoclonal antibodies (mAbs) are decorated with complex glycans that determine not only their efficacy but also other critical parameters such as in vivo half-life, stability and antigenicity. Read more
Selection and evaluation of new universal influenza vaccine candidates using monoclonal antibodies and digitally designed HA and NA libraries & pseudotype virus screens
Universal influenza vaccines are a major global R&D vaccine priority. The Temperton (ORCID. https://orcid.org/0000-0002-7978-3815). Read more
Selection and evaluation of new universal influenza vaccine candidates using monoclonal antibodies and digitally designed HA and NA libraries & pseudotype virus screens
Universal influenza vaccines are a major global R&D vaccine priority. The Temperton (ORCID. https://orcid.org/0000-0002-7978-3815). Read more
Electrochemical detection of unlabelled antibodies to SARS-CoV-2 variations based on carbon derivative electrodes
The investigation of infection-related biomarkers has become crucial after the outbreak of covid-19 in 2019. For this reason, research is vital to responding to the changing situation, caused by mutation of the virus, and the impacts of infection after it has occurred. . Read more
Controlling parasitic varroa mites and viral disease in honey bee hives using immunotherapy
One of the greatest threats and costs for the honey bee industry is the parasitic varroa mite and the viral diseases the parasite spreads. Read more
Generation of human cytomegalovirus-pseudotyped particles and development of systems for the study of viral cell entry mechanisms, neutralizing antibody responses to infection and vaccination, and testing of potential novel therapeutics
Overview. Human cytomegalovirus (HCMV) establishes lifelong infections of the host with >60% infected across the globe. In healthy children and adults HCMV produces mild symptoms like influenza or mononucleosis. Read more
Generation of human cytomegalovirus-pseudotyped particles and development of systems for the study of viral cell entry mechanisms, neutralizing antibody responses to infection and vaccination, and testing of potential novel therapeutics
Overview. Human cytomegalovirus (HCMV) establishes lifelong infections of the host with >60% infected across the globe. In healthy children and adults HCMV produces mild symptoms like influenza or mononucleosis. Read more
Computational modelling to understand the key determinants of placental antibody transfer
Supervisory Team. Bram Sengers (SoE), Chrissie Jones (Medicine), Rohan Lewis (Medicine). Project description. Read more
A new approach to CRISPR-Cas adaptation and the discovery of host accessory-proteins
Bacteria provide many health benefits and eco-environmental services. Although physically simple, they have a sophisticated immune system, CRISPR-Cas. Read more
The Creation of Anti-Viral Plastic Nanobodies for Diagnostics and Therapeutics via Molecular Imprinting of Synthetic Polymers
Overview. The need to quickly generate new diagnostic tools and therapies in the battle against viral diseases has been highlighted recently by the continuing global pandemic caused by the SARS-CoV-2 virus. Read more
The Creation of Anti-Viral Plastic Nanobodies for Diagnostics and Therapeutics via Molecular Imprinting of Synthetic Polymers
Overview. The need to quickly generate new diagnostic tools and therapies in the battle against viral diseases has been highlighted recently by the continuing global pandemic caused by the SARS-CoV-2 virus. Read more
Engineering biosensors for the detection of bacterial proteins
Superbug outbreaks are more likely to occur in a healthcare environment and are causing an increasing number of deaths every year. Read more
Antibody Purification
We are developing a non-chromatographic, ligand-free general platform for antibody purification that is simple to implement, easy to upscale, cost-effective, and as such may provide a true alternative to the gold-standard technology. Read more
Characterising mechanisms of mononuclear phagocyte recruitment to the lung and their localisation specific function in respiratory viral infection.
Research Group:
Edinburgh Infectious Diseases
Project offered for Ker Memorial PhD Studentship in Infectious Diseases. Despite upcoming modern vaccine technologies, respiratory viral infections will remain a key healthcare burden for many years, requiring the development of prophylactic interventions for high-risk individuals and therapies. Read more