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antibody PhD Projects, Programmes & Scholarships

We have 51 antibody PhD Projects, Programmes & Scholarships



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We have 51 antibody PhD Projects, Programmes & Scholarships

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Antibody Purification

We are developing a non-chromatographic, ligand-free general platform for antibody purification that is simple to implement, easy to upscale, cost-effective, and as such may provide a true alternative to the gold-standard technology. Read more

Obtaining a molecular understanding of antibody secretion

Plasma cells are the antibody producing cells of the immune system so are vital for fighting infection. Plasma cells secrete hundreds of millions of antibody molecules per day and this is achieved by a dramatic upregulation of their biosynthetic pathway. Read more

New synthetic methodology developments for innovations in antibody drug conjugate (ADC) linker design

The project will develop new synthetic methodologies for the overall aim of delivering novel chemical linkers for ADCs. This is a collaboration with AstraZeneca scientists who are world-leaders in ADC technology. Read more

Development of antibody-drug conjugates (ADCs) for oncology indications

  Research Group: Institute of Cancer Therapeutics
A major challenge in cancer therapy is to develop therapeutic agents that selectively target tumour cells but are not harmful to normal tissue. Read more

Defining B cell gene signatures associated with higher affinity antibodies

This project will use well-established wet lab techniques but require the development of bespoke scripts and computational analysis pipelines and would suit a student with prior experience or a clear aptitude for bioinformatics. Read more

Generating a new bioconjugation agent for RNA analysis

  Research Group: Midlands Integrative Biosciences Training Partnership (MIBTP)
a) Background to project. There is a need for efficient chemical reactions which permit the attachment of chemical groups such as dyes, fluorescent markers, drug molecules etc., to large biomolecules such as proteins, RNA or DNA. Read more

New tools for efficient recombinant protein production

Recombinant protein production (RPP) is a key tool in the production of biopharmaceuticals such as insulin as well as in basic biomedical and molecular biology research. Read more

Development of novel pulmonary biotherapeutics for chronic inflammatory airway diseases

This cross-disciplinary PhD project is between the School of Biomedical Science at University of West London (UWL) and School of Pharmacy at UCL to investigate the feasibility of developing inhalation form of biotherapeutics for severe chronic inflammatory diseases. Read more

Pioneering a novel cancer targeting glyco-immunotherapy strategy

Background. Human cells are coated in a thick layer of sticky sugars called the glycocalyx. Uniquely cancer cells are covered with an excess of the human ‘sialic acid’ sugar Neu5Ac, and this has been shown to ‘camouflage’ the cells from the immune system. Read more
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EASTBIO CASE Exploring bottlenecks in biopharmaceutical production using subcellular fractionation of Chinese hamster ovary cells

  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
Chinese hamster ovary (CHO) cells are the chassis of choice for the production of biopharmaceuticals, such as monoclonal antibodies, with yields of up to 10 gL-1. Read more

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