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antibody PhD Projects, Programs & Scholarships

We have 44 antibody PhD Projects, Programs & Scholarships

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We have 44 antibody PhD Projects, Programs & Scholarships

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Correcting ageing defects in B lymphocyte development and antibody production

B lymphocytes in the adaptive immune system generate billions of antibodies to combat the countless pathogens we encounter. This key function underpins the normal immune response, while defects contribute to poor response to infection and vaccination in elderly people. Read more

Investigating how RNA helicase activity modulates antibody immunity

Adaptive immunity is characterized by gradual, though highly specific and effective immune responses against pathogens. B-cells are responsible for the production of a diverse repertoire of antibodies, through class switch recombination (CSR) and somatic hypermutation (SHM). Read more

Cancer therapy endocytosis

This is a project which aims to investigate how tumours and normal tissue internalise drugs such as cancer therapy antibodies in real in vivo models and in patients. Read more

Engineered non-antibody binding protein Affimers for cryo-electron microscopy and tomography

This project is about developing non-antibody binding proteins to determine unsolved protein structures using cryo-EM. We will focus on determining protein structures of the centrosome, the largest membrane-less protein complex in animal cells. Read more

Suppression of T cell immunity and antibody production during virus infection and sepsis

Summary. The generation of protective antibodies against infection is dependent on “help” from CD4+ T follicular helper (TFH) cells which are elicited in response to bacteria and viruses, such as influenza and SARS CoV-2. Read more

Pancoronavirus neutralizing antibodies

Talented and motivated students passionate about doing research are invited to apply for this PhD position. The successful applicant will join the Crick PhD Programme in September 2022 and will register for their PhD at one of the Crick partner universities (King’s College London). Read more

Precise, peptide-directed loading of drugs onto therapeutic antibodies for targeted imaging and treatment of tumors.

The PhD project aims to develop a non-covalent technology for loading small molecules and therapeutic enzymes onto monoclonal antibodies thus addressing issues in preparations of antibody-drug conjugates, such as poor yields and non-specific conjugation of the drugs resulting in compromised immunoaffinity. Read more

Lighting up biotherapeutics (SACHDEVA_U22DTP)

Over the last decade, several antibody-based biotherapeutics have been developed for treatment of cancer. These antibodies, often marketed as “targeted therapeutics”, bind to cell surface receptors on cancer cells and direct them towards apoptosis (programmed cell death). Read more

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