apoptosis PhD Projects, Programs & Scholarships

We have 30 apoptosis PhD Projects, Programs & Scholarships

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Showing 1 to 10 of 30 PhDs

Characterisation of cell death mechanisms in cancer: protein interactions in p53/PERP-mediated apoptosis

University of Liverpool
Institute of Ageing and Chronic Disease

Prof L Paraoan, Dr I Prior

Applications accepted all year round

Apoptosis or programmed cell death is a tightly regulated intrinsic process of programmed cell death used by cells in all multicellular organisms, including humans, to control tissue homeostasis or to initiate their own death following malfunction or damage beyond repair.

Details

PhD Research Project Type/Funding

MRC DiMeN Doctoral Training Partnership: Application of data science to inherited genetic variants of apoptosis genes and susceptibility to breast cancer

University of Sheffield
MRC DiMeN Doctoral Training Partnership

Prof A Cox, Dr A Droop, Dr K Walters

Application Deadline: 21 January 2019

The identification of the breast and ovarian cancer genes BRCA1 and BRCA2 two decades ago has resulted in both improved risk assessment for patients and the use of PARP-inhibitors for treatment.

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PhD Research Project Type/Funding

Application of data science to inherited genetic variants of apoptosis genes and susceptibility to breast cancer

University of Sheffield
Oncology and Metabolism

Prof A Cox, Dr K Walters

Application Deadline: 23 January 2019

Background. The identification of the breast and ovarian cancer genes BRCA1 and BRCA2 two decades ago has resulted in both improved patient risk assessment and the use of PARP-inhibitors for treatment.

Details

PhD Research Project Type/Funding

Regulation of apoptosis-induced compensatory cell proliferation and its implications for cancer and tissue regeneration

University of Birmingham
School of Biosciences

Dr Y Fan

Applications accepted all year round

In multi-cellular organisms, coordinated cell death (e.g. apoptosis) and cell replacement is critical for tissue recovery in response to stress or damage.

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PhD Research Project Type/Funding

Targeting the P2X7 purinergic receptor in melanoma (STOKESLU19SF)

University of East Anglia
School of Pharmacy

Dr L Stokes, Dr C Morris

Application Deadline: 31 May 2019

There is much research into trying to regain control of cell proliferation or cell death (apoptosis) in cancer. Different strategies exist to do this and a multitude of individual receptor targets are being identified in tumour cell lines and primary cells.

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PhD Research Project Type/Funding

The mechanism and intervention of acute renal injury

University of Leicester
Department of Infection Immunity & Inflammation

Dr B Yang, Prof N J Brunskill

Applications accepted all year round

The Kidney Lifestyle research team run a broad translational research into Acute kidney injury (AKI). This has high mortality with 13 million incidences globally contributing to 1.7 million deaths every year.

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PhD Research Project Type/Funding

(A*STAR) Analysis of the role of microRNAs in the regulation of NF-kappaB dynamics and function

University of Manchester
Faculty of Biology, Medicine and Health

Prof M White, Dr A P Gilmore

Application Deadline: 31 January 2019

The project will investigate the control of NF-kB. This transcription factor is one of most important cell signalling systems in the body that controls inflammation and cell fate.

Details

PhD Research Project Type/Funding

Analysis of the role of microRNAs in the regulation of NF-kappaB dynamics and function

University of Manchester
Faculty of Biology, Medicine and Health

Prof M White, Dr A P Gilmore

Applications accepted all year round

NF-κB is one of most important cell signalling systems in the body and controls inflammation and cell fate. NF-κB signalling involves complex dynamics involving oscillations of the NF-κB complex between the nucleus and cytoplasm in activated cells.

Details

PhD Research Project Type/Funding

Synthesis and Anti-Cancer Evaluation of New Heterocyclic Quinones

Kingston University
Faculty of Science, Engineering and Computing

Prof F Aldabbagh, Dr N Hill

Applications accepted all year round

The group has published on small molecules with specificity towards hypoxic cells associated with solid tumours, reductase enzymes over-expressed in cancer, as well as, aziridines that induce hypersensitivity from Fanconi anaemia cells and those carrying mutations in the BRCA (Breast Cancer Susceptibility) genes.

Details

PhD Research Project Type/Funding

Elucidating the interplay between mitochondrial dynamics, organelle contact sites and metabolic (re)programming (On the University’s application portal, please select "PhD in Medical Science at the MRC Mitochondrial Biology Unit").

Medical Research Council (Cambridge)
Mitochondrial Biology Unit

Dr J Prudent

Application Deadline: 30 June 2019

Mitochondria house hundreds of biochemical reactions involved in processes critical for the survival and homeostatic adaptation of the cell.

Details