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apoptosis PhD Projects, Programs & Scholarships

We have 31 apoptosis PhD Projects, Programs & Scholarships

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  Redeploying Rucaparib: Can PARP inhibitors alter deregulated cellular bioenergetics and overcome apoptosis resistance in cancer? (SF20/APP/WALDEN)
  Dr H Walden
Applications accepted all year round

Funding Type

PhD Type

Poly(ADP-ribose) polymerase inhibitors (PARPi) have received huge attention in oncology over recent years. They are FDA approved for use in BRCA1/2 defective breast and ovarian cancers with absent or dysfunctional homologous recombination repair function.
  Regulation of apoptosis-induced compensatory cell proliferation and its implications for cancer and tissue regeneration
  Dr Y Fan
Applications accepted all year round

Funding Type

PhD Type

In multi-cellular organisms, coordinated cell death (e.g. apoptosis) and cell replacement is critical for tissue recovery in response to stress or damage.
  The role of polyploidy across the lifespan of epithelial tissues
  Dr K Panfilio, Dr A Pires da Silva
Application Deadline: 7 June 2020

Funding Type

PhD Type

Epithelial tissues are essential structures in animals, creating compartments and barriers such as the skin and lining of the gut.
  Characterisation of cell death pathways upon activation of the endoplasmic reticulum stress sensor IRE1alpha
  Dr M Schroeder
Applications accepted all year round

Funding Type

PhD Type

A self-funded PhD project to investigate cell death pathways activated by endoplasmic reticulum (ER) stress is available in the group of Dr.
  USP17 as a cancer therapeutic target
  Dr J Burrows
Applications accepted all year round

Funding Type

PhD Type

USP17 is over-expressed in a range of primary tumours including NSCLC, breast, colorectal, cervical, ovarian and osteosarcoma and its depletion has been shown to block the growth of cells from all these cancer types.
  A role for the microbiome in the response of skin to ultraviolet radiation
  Prof C A O'Neill, Prof A McBain
Applications accepted all year round

Funding Type

PhD Type

During the last decade, it has become clear that physiological health depends to a large extent, on the body’s relationship with its microbiome (reviewed in 1).
  Understanding the impact of placental aging on placental function
  Dr A Heazell, Dr M Dilworth, Dr M Desforges
Applications accepted all year round

Funding Type

PhD Type

Prolonged pregnancy (>41 weeks gestation) is associated with an increase in perinatal mortality (the death of a baby before or shortly after birth) from a nadir of 1 per 1,000 births at 39 weeks’ to 3 per 1,000 births at 41 weeks which continues to rise beyond this time.
  Metabolic reprogramming in cancer: starving tumors of essential nutrients to promote cell death
  Dr S Papa
Applications accepted all year round

Funding Type

PhD Type

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow.
  An intelligent scheme to identify novel drug targets through analysing the DNA repairome in drug resistant cancer?
  Research Group: Biomedical Research Group
  Prof C Parris
Applications accepted all year round

Funding Type

PhD Type

Research Group. Biomedical Research Group. https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/biomedical.
  Synthesis and Anti-Cancer Evaluation of New Heterocyclic Quinones
  Prof F Aldabbagh, Dr N Hill
Applications accepted all year round

Funding Type

PhD Type

The group has published on small molecules with specificity towards hypoxic cells associated with solid tumours, reductase enzymes over-expressed in cancer, as well as, aziridines that induce hypersensitivity from Fanconi anaemia cells and those carrying mutations in the BRCA (Breast Cancer Susceptibility) genes.
  Fully Funded PhD Position in the Area of Coherent Raman Spectroscopy/Microscopy for biomedical applications
  Dr B Hennelly
Application Deadline: 5 June 2020

Funding Type

PhD Type

The objective of this project is to design, build, and test a proof-of-concept label-free flow cytometer based on the current state-of-the-art for high-speed broadband coherent spectroscopy.
  Elucidating the interplay between mitochondrial dynamics, organelle contact sites and metabolic (re)programming (On the University’s application portal, please select "PhD in Medical Science at the MRC Mitochondrial Biology Unit").
  Dr J Prudent
Application Deadline: 30 June 2020

Funding Type

PhD Type

Mitochondria house hundreds of biochemical reactions involved in processes critical for the survival and homeostatic adaptation of the cell.
  The role of the breast microenvironment in suppressing early cancer invasion
  Assoc Prof B Parker, Dr D Zanker
Applications accepted all year round

Funding Type

PhD Type

Ductal carcinoma in situ (DCIS) is a pre-invasive stage of breast cancer, whereby the tumour cells remain restrained by myoepithelial cells that surround breast ducts.
  Modelling of Oral Neutrophil Epithelial interactions
  Dr E Hagi-Pavli
Applications accepted all year round

Funding Type

PhD Type

Background and Clinical Significance. Neutrophils are an important and vital cellular component of the innate immune system providing rapid protection against microbial invasion.
  Bioorthogonal Chemistry and Fluorescent Post-Labeling for Real-Time Tracking of a Platinum-based Anticancer Drug
  Dr D Griffith, Dr D O’Shea
Applications accepted all year round

Funding Type

PhD Type

Metal-based drugs have a wide range of medicinal applications and are routinely used clinically as therapeutic and diagnostic agents.
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