Imperial College London Featured PhD Programmes
Gdansk University of Technology Featured PhD Programmes
Queen’s University Belfast Featured PhD Programmes

apoptosis PhD Projects, Programmes & Scholarships

We have 36 apoptosis PhD Projects, Programmes & Scholarships

Discipline

Discipline

All disciplines

Location

Location

All locations

Institution

Institution

All Institutions

PhD Type

PhD Type

All PhD Types

Funding

Funding

All Funding


We have 36 apoptosis PhD Projects, Programmes & Scholarships

PhD saved successfully

Understanding apoptotic heterogeneity in cell populations

Apoptosis is a form of programmed cell death that occurs in response to stress such as genomic damage. The decision to initiate apoptosis is taken at the outer mitochondrial membrane (OMM) by members of the Bcl-2 family of proteins. Read more

Is there a Role for Activated Akt in Palatogenesis?

Main Aim. The project will use a medial edge epithelial (MEE) cell line as an in vitro model. These cells will be used to investigate the effects of exogenous TGFβ-3 and activation of Akt on cell migration, epithelial to mesenchymal transition (EMT) and apoptosis. Read more

Viral regulation of host cell DNA damage response pathways

Human adenoviruses are small non-enveloped viruses and possess a linear, double-stranded DNA genome. Adenovirus has long been used as a tool to dissect the molecular basis of key biological processes such as growth, differentiation and death. Read more

Metabolic reprogramming in cancer: starving tumors of essential nutrients to promote cell death

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more

Macrophage driven therapy resistance in AML: from macrophage subset characterisation to therapeutic targeting.

  Research Group: Molecular Mechanisms and Long Term Conditions
Reference. SHLS20065. Background. Acute Myeloid Leukaemia (AML) is a common blood cancer in adults; with its incidence increasing with age, AML cases are predicted to double by 2030. Read more

Novel anti-pathogen regulatory mechanisms driven by Human Guanylate Binding Proteins

Human GBPs are a family of seven ~65kDa GTPases whose expression is upregulated by IFNg, for example during an infection. All mammalian GBPs contain a GTPase domain and a C-terminal helical region. Read more

Universal genome editing strategies for ataxia telangiectasia

Ataxia telangiectasia (A-T) is a severe autosomal recessive genetic disease caused by mutations in the ATM gene, which lead to cerebellar degeneration, cancer susceptibility and immunodeficiency. Read more

Targeting protein acetylation to reduce microglia activation in neurodegenerative disorders

Recently, inhibitors of histone deacetylase enzymes (HDACs) have been identified as having potential therapeutic value for a range of neuronal disorders including Alzheimer’s disease, dementia and stroke [1, 2]. Read more

PhD in Vision Sciences: Evaluating functional outcomes of novel therapies for mitochondrial optic neuropathy using ultra-high resolution multi-electrode array

Mitochondrial optic neuropathies result in blindness and are currently untreatable. They arise as a consequence of genetic mutations in either mitochondrial or nuclear DNA and share the common characteristic of primarily affecting retinal ganglion cell (RGC) survival. Read more

Filtering Results