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apoptosis PhD Projects, Programs & Scholarships

We have 39 apoptosis PhD Projects, Programs & Scholarships

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  Investigation of mechanistic links between metabolic stress, inflammation and apoptosis in cartilage damage in osteoarthritis
University of Bristol Faculty of Health Sciences
  Dr M Sharif
Applications accepted all year round
Osteoarthritis (OA) is the most common joint disease in the elderly population, causing significant pain and disability. It is estimated that by by 2020, OA will be the forth leading cause of disability in the world.
Details
Type/Funding
  Characterisation of cell death mechanisms in cancer: protein interactions in p53/PERP-mediated apoptosis
University of Liverpool Institute of Ageing and Chronic Disease
  Prof L Paraoan, Dr I Prior
Applications accepted all year round
Apoptosis or programmed cell death is a tightly regulated intrinsic process of programmed cell death used by cells in all multicellular organisms, including humans, to control tissue homeostasis or to initiate their own death following malfunction or damage beyond repair.
Details
Type/Funding
  MRC DiMeN Doctoral Training Partnership: Application of data science to inherited genetic variants of apoptosis genes and susceptibility to breast cancer
University of Sheffield MRC DiMeN Doctoral Training Partnership
  Prof A Cox, Dr A Droop, Dr K Walters
Application Deadline: 21 January 2019
The identification of the breast and ovarian cancer genes BRCA1 and BRCA2 two decades ago has resulted in both improved risk assessment for patients and the use of PARP-inhibitors for treatment.
Details
Type/Funding
  Regulation of apoptosis-induced compensatory cell proliferation and its implications for cancer and tissue regeneration
University of Birmingham School of Biosciences
  Dr Y Fan
Applications accepted all year round
In multi-cellular organisms, coordinated cell death (e.g. apoptosis) and cell replacement is critical for tissue recovery in response to stress or damage.
Details
Type/Funding
  BBSRC MIBTP: Dead cells can talk – understanding the roles of apoptosis in tissue regeneration and growth control
University of Birmingham School of Biosciences
  Research Group: BBSRC MIBTP
  Dr Y Fan, Dr N A Hotchin
Application Deadline: 6 January 2019
Apoptosis, a major form of programmed cell death, is frequently activated in response to stress to remove damaged cells in multi-cellular organisms.
Details
Type/Funding
  Targeting the P2X7 purinergic receptor in melanoma (STOKESLU19SF)
University of East Anglia School of Pharmacy
  Dr L Stokes, Dr C Morris
Application Deadline: 31 May 2019
There is much research into trying to regain control of cell proliferation or cell death (apoptosis) in cancer. Different strategies exist to do this and a multitude of individual receptor targets are being identified in tumour cell lines and primary cells.
Details
Type/Funding
  Structural biology of Apoptosis Signal-regulating Kinases
University of Otago Biochemistry Department
  Dr PD Mace
Applications accepted all year round
A PhD Project is available for a domestic or international candidate to study the structure and function of Apoptosis Signal-regulating Kinases (ASK1–3).
Details
Type/Funding
  The mechanism and intervention of acute renal injury
University of Leicester Department of Infection Immunity & Inflammation
  Dr B Yang, Prof N J Brunskill
Applications accepted all year round
The Kidney Lifestyle research team run a broad translational research into Acute kidney injury (AKI). This has high mortality with 13 million incidences globally contributing to 1.7 million deaths every year.
Details
Type/Funding
  Analysis of the role of microRNAs in the regulation of NF-kappaB dynamics and function
University of Manchester Faculty of Biology, Medicine and Health
  Prof M White, Dr A P Gilmore
Applications accepted all year round
NF-κB is one of most important cell signalling systems in the body and controls inflammation and cell fate. NF-κB signalling involves complex dynamics involving oscillations of the NF-κB complex between the nucleus and cytoplasm in activated cells.
Details
Type/Funding
  BAOU18CPRT Anti-cancer activities of dietary isothiocyanates
University of East Anglia Norwich Medical School
  Dr Y Bao
Application Deadline: 20 September 2019
Sulforaphane (SFN) is an isothiocyanate (ITC) derived from glucosinolate (glucoraphanin) under the action of myrosinase when the plant tissue is damaged or chewed.
Details
Type/Funding
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