Rheumatoid arthritis (RA) is an immune mediated inflammatory disease which constitutes a major global healthcare challenge as it causes significant disability and pain. Read more
Inflammatory arthritis (IA) can result from non-autoimmune diseases (like crystal arthritis) and from autoimmune diseases like rheumatoid arthritis (RA) and spondyloarthropathies (inc. Read more
Rheumatoid Arthritis (RA) is a chronic autoimmune disease that significantly impacts the quality of life of those affected, particularly middle aged and older women. Read more
Juvenile idiopathic arthritis (JIA) is an autoimmune inflammatory arthritis with disease onset before the age of 16. Children and young people with this condition develop painful swollen joints and untreated it can lead to long term disability. It may also be associated with comorbid conditions such as uveitis. Read more
Inflammatory arthritis (IA) can result from non-autoimmune diseases (like crystal arthritis) and from autoimmune diseases like rheumatoid arthritis (RA) and spondyloarthropathies. Read more
Juvenile idiopathic arthritis (JIA) is a chronic inflammatory arthritis affecting children and young people with an age of disease onset less than 16 years of age. Read more
This DPhil in Clinical Epidemiology and Medical Statistics will include a 3-year project focussing on target trial emulation studies to generate real-world evidence for arthritis and orthopaedic treatments using de-identified, routinely-collected data from primary and secondary care in the UK and across Europe. Read more
Fibrotic diseases affect multiple organ systems, increasing global morbidity and mortality1. Fibrosis is the final common pathway for a wide range of diseases affecting joint soft tissues including tendons, ligaments and synovial tissues2,3. Read more
mRNA based technologies have revolutionised vaccines and have the potential to modulate not just immunity to pathogens but also re-engineer immune responses to resolve chronic inflammatory disease. Read more
Mesenchymal stem cells (MSCs) are responsible for the repair of damaged tissue following injury and disease as well as moderating innate and adaptive immune responses and regulation of self-tolerance and tissue homeostasis. Read more
This full-time DPhil post at the Botnar Institute will use cutting edge laboratory and computational methods to interrogate the mechanisms underlying shoulder pain. Read more
Summary. Mood disorders (MDs), e.g. depression, affect over one billion people worldwide. MDs show a bidirectional relationship with systemic inflammation, a key component in the pathophysiology of autoimmune disorders (ADs), e.g. Read more
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