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assay PhD Projects, Programmes & Scholarships
We have 64 assay PhD Projects, Programmes & Scholarships
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Development of an isolated glomerular albumin permeability assay to high throughput for drug screening in human glomerular disease
Rationale. There is an urgent need to identify new clinical treatments for those with kidney disease. It is also critical to have a screening system to enable us to identify novel drugs that are relevant to humans. Read more
Selection and evaluation of new universal influenza vaccine candidates using monoclonal antibodies and digitally designed HA and NA libraries & pseudotype virus screens
Universal influenza vaccines are a major global R&D vaccine priority. The Temperton (ORCID. https://orcid.org/0000-0002-7978-3815). Read more
Selection and evaluation of new universal influenza vaccine candidates using monoclonal antibodies and digitally designed HA and NA libraries & pseudotype virus screens
Universal influenza vaccines are a major global R&D vaccine priority. The Temperton (ORCID. https://orcid.org/0000-0002-7978-3815). Read more
SELF-FUNDING MSc BY RESEARCH PROJECT. Approach - Avoidance foraging; a novel and ethological rodent assay to evaluate anxiety-like behaviour and the brain networks that support it
The Group. This Masters by Research (MSc) is entirely laboratory based giving you the best possible experience of life as a researcher as well enough time to develop skills and techniques. Read more
Biomarkers of Genotoxic and Reprotoxic Effects after chemical exposure in vitro in human cells
Research Group:
Chemistry and Biosciences
In human monitoring, procedure measurement obtained from endpoints from endpoints to determine genetic damage are sometimes referred to as biomarkers. Read more
Stem Cell Exosomes - Important communicators with therapeutic potential on the dental pulp
The regenerative potential of mesenchymal stem cells has recently been attributed to exosomes, defined as extracellular vesicles of endocytic origin. Read more
Therapeutic targeting of chemokines in inflammation
Protein interactions underlie most biological processes but are challenging to target using small molecule drugs. Many protein interactions are mediated by short-linear-interacting motifs (SLiMs) that range from 3-12 amino acid residues (1, 2). Read more
Fragment-Based Lead Generation of Small Molecule Inhibitors of the Nsp3 Macrodomain in SARS-CoV-2 – Towards New Antivirals for the Treatment of COVID-19
Fragment-Based Lead Generation of Small Molecule Inhibitors of the Nsp3 Macrodomain in SARS-CoV-2 – Towards New Antivirals for the Treatment of COVID-19. Read more
Project at University of Reading - A New Approach to the Production of Cultured Meat with Enhanced Texture
Project description. Future food production needs to meet a growing demand for food and changing diets, as the human population is predicted to reach 9 billion by 2050. Read more
Link between inflammation blood clots and the perturbed vessel wall
This project is one of 17 four year PhD Studentships funded by Medical Research Scotland (. https://www.medicalresearchscotland.org.uk. Read more
Identification of cis- and trans-acting genetic modifiers of somatic expansion as novel therapeutic targets in the repeat expansion disorders
At least 40 human disorders, including Huntington disease and myotonic dystrophy, are caused by the expansion of a simple sequence repeat [1]. Read more
Evaluation of combination therapies targeting DNA damage repair signalling pathways in acute myeloid leukaemia
Acute myeloid leukaemia (AML) is an aggressive cancer affecting mostly adult and elderly patients. It has a very poor 5-year survival of <20% in the UK. Read more
Development of novel small molecule inhibitors of Gremlin1, a pathogenic driver of diabetic kidney disease
Gremlin1 is a secreted protein antagonist of bone morphogenetic proteins (BMPs) that regulated developmental processes such as limb and kidney formation. Read more
Detection of Pathogens Using Bionanosensors combined with Surface Enhanced Raman Scattering (SERS)
Rapid detection of bacteria is crucial for the health of the general public as the threat of infectious disease is dramatically increasing. Read more
4-year PhD Studentship: Endothelial glycocalyx damage as a therapeutic target in cardiopulmonary bypass associated acute kidney injury
Patients undergoing cardiopulmonary bypass (CPB) often develop acute kidney injury (AKI) caused by myocardial ischemia reperfusion injury (MIRI). Read more