assay PhD Projects, Programmes & Scholarships

Discovery of New Treatments for Parkinson’s disease

Cardiff University Cardiff School of Pharmacy and Pharmaceutical Sciences

Summary. Parkinson’s disease (PD) is the second most common neurological disease in the world. Current PD therapies and medical interventions are very limited and only address the symptoms of this disease highlighting the need for new and effective treatments for this disease. Read more

Supervisor: Dr Y Mehellou

Year round applications PhD Research Project Self-Funded PhD Students Only

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Skeletal Muscle Organoid Models for Genetic Mitochondrial Disease (ref: SF22/HLS/APP/Johnson)

Northumbria University Faculty of Health and Life Sciences

Genetic mitochondrial diseases are both clinically and genetically heterogeneous. Read more

Supervisor: Dr S Johnson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Developing 3D models to understand how interactions between bacterial biofilm and the host environment impact antimicrobial efficacy in a chronic infected wound

Cardiff Metropolitan University Cardiff School of Sport and Health Sciences

2.8 million people in the UK have a chronic wound which persist for months or years, causing pain, isolation, odour, and decreased mobility; patients with chronic wounds regularly report a deterioration in quality of life. Polymicrobial biofilms are present in greater than 70% of chronic wounds, making effective treatment incredibly challenging. Read more

Supervisors: Dr S Maddocks, Dr M Beeton, Dr R Aicheler, Prof L Robins

Year round applications PhD Research Project Self-Funded PhD Students Only

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The use of gaseous and aqueous ozone in the prevention and remediation of biofilms within food manufacturing environments

Cardiff Metropolitan University Cardiff School of Sport and Health Sciences

Biofilms can be classified as an assembly of surface associated microbial cells that are enclosed in an extracellular polymeric substance matrix. Read more

Supervisor: Dr J Blaxland

Year round applications PhD Research Project Self-Funded PhD Students Only

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Exploring Myxobacteria as live antibiotics against pathogenic bacteria

Cardiff Metropolitan University Cardiff School of Sport and Health Sciences

Multi-drug resistant (MDR) bacteria have been identified as a global threat to humanity, limiting therapeutic options. The search for new antibiotics lags far behind the occurrence of MDR bacteria with no new antibiotics brought to the clinic for over 15 years. Read more

Supervisors: Dr P Livingstone, Dr S Maddocks

Year round applications PhD Research Project Self-Funded PhD Students Only

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Generation of human cytomegalovirus-pseudotyped particles and development of systems for the study of viral cell entry mechanisms, neutralizing antibody responses to infection and vaccination, and testing of potential novel therapeutics

University of Greenwich School of Pharmacy (Medway Campus)

Overview. Human cytomegalovirus (HCMV) establishes lifelong infections of the host with >60% infected across the globe. In healthy children and adults HCMV produces mild symptoms like influenza or mononucleosis. Read more

Supervisors: Dr S Scott, Dr N Temperton, Dr M Reeves

Year round applications PhD Research Project Self-Funded PhD Students Only

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Generation of human cytomegalovirus-pseudotyped particles and development of systems for the study of viral cell entry mechanisms, neutralizing antibody responses to infection and vaccination, and testing of potential novel therapeutics

University of Kent Medway School of Pharmacy

Overview. Human cytomegalovirus (HCMV) establishes lifelong infections of the host with >60% infected across the globe. In healthy children and adults HCMV produces mild symptoms like influenza or mononucleosis. Read more

Supervisors: Dr S Scott, Dr N Temperton, Dr M Reeves

Year round applications PhD Research Project Self-Funded PhD Students Only

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Translational Medicine: Understanding the mechanism(s) of resistance to EPA to personalise therapy and improve outcome

University of Leeds Faculty of Medicine and Health

Advanced colorectal cancer (CRC) is the UK’s second most lethal cancer, with limited treatment options for unresectable metastatic tumours. Read more

Supervisors: Dr MA Volpato, Prof M Hull

Year round applications PhD Research Project Self-Funded PhD Students Only

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Clinical Gastroenterology: The regulation of GDH expression in Clostridioides difficile

University of Leeds Faculty of Medicine and Health

Clostridioides difficile infection (CDI), the most common cause of infective antibiotic-associated diarrhea in the western world, is diagnosed by a combination of tests that firstly detect the organism, then the toxins that it produces (Planche 2013). Read more

Supervisors: Prof M Wilcox, Dr K Davies, Dr A Buckley

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer: Why and how do brain tumour cells invade ‘mini-brains’?

University of Leeds Faculty of Medicine and Health

Globally, nearly 189,000 people die each year as a result of brain cancer and around 250,000 people are diagnosed with a malignant brain tumour (umbrella name. Read more

Supervisors: Dr H Wurdak, Dr R Mathew

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer: Inhibiting cell metabolism to enhance tumour cell death

University of Leeds Faculty of Medicine and Health

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more

Supervisors: Dr S Papa, Dr R Tooze

Year round applications PhD Research Project Self-Funded PhD Students Only

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Identification and characterisation of bacteriocins from environmental samples active against strains of Clostridium difficile.

University of Nottingham School of Life Sciences

Clostridiodes difficile is a cause of neonatal enteritis in livestock such as pigs, cattle and horses. Affected animals develop respiratory problems, abdominal distention and bloody diarrhoea leading to weight loss and in extreme cases mortality. Read more

Supervisors: Dr C Penfold, Dr K Winzer

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 72 assay PhD Projects, Programmes & Scholarships

assay PhD Projects, Programmes & Scholarships

We have 72 assay PhD Projects, Programmes & Scholarships

Discovery of New Treatments for Parkinson’s disease

Skeletal Muscle Organoid Models for Genetic Mitochondrial Disease (ref: SF22/HLS/APP/Johnson)

Developing 3D models to understand how interactions between bacterial biofilm and the host environment impact antimicrobial efficacy in a chronic infected wound

The use of gaseous and aqueous ozone in the prevention and remediation of biofilms within food manufacturing environments

Exploring Myxobacteria as live antibiotics against pathogenic bacteria

Generation of human cytomegalovirus-pseudotyped particles and development of systems for the study of viral cell entry mechanisms, neutralizing antibody responses to infection and vaccination, and testing of potential novel therapeutics

Generation of human cytomegalovirus-pseudotyped particles and development of systems for the study of viral cell entry mechanisms, neutralizing antibody responses to infection and vaccination, and testing of potential novel therapeutics

Translational Medicine: Understanding the mechanism(s) of resistance to EPA to personalise therapy and improve outcome

Clinical Gastroenterology: The regulation of GDH expression in Clostridioides difficile

Cancer: Why and how do brain tumour cells invade ‘mini-brains’?

Cancer: Inhibiting cell metabolism to enhance tumour cell death

Identification and characterisation of bacteriocins from environmental samples active against strains of Clostridium difficile.

We have 72 assay PhD Projects, Programmes & Scholarships

assay PhD Projects, Programmes & Scholarships

We have 72 assay PhD Projects, Programmes & Scholarships

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