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We have 9 autophagy PhD Projects, Programmes & Scholarships

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autophagy PhD Projects, Programmes & Scholarships

We have 9 autophagy PhD Projects, Programmes & Scholarships

Investigating the Roles for deSUMOylation Enzyme SENP3 in Autophagy Impaired by α-synuclein

Aggregation of α-synuclein protein in neuronal cells has been strongly implicated in the pathogenesis of neurodegenerative disorders (Synucleinopathies) including Parkinson's disease and dementia with Lewy bodies. Read more

Adeno-associated virus-based gene therapy for Mucolipidosis IV disorder

Project ID. SST_SHiMR_13. Mucolipidosis IV (MLIV, OMIM # 252650) is an autosomal recessive neurodegenerative lysosomal storage disorder characterized by intellectual disability, psychomotor retardation, hypotonia, corneal opacity, retinal degeneration, blindness, and limited or absent speech. Read more

Cellular protein quality control in diabetes-associated heart disease: The insight into mechanisms and therapeutic potentials

Cardiovascular complications are the leading causes of diabetes mortality. With the exception of vascular and valvular injuries, diabetic cardiomyopathy (DCM) is a distinct myocardial disease, which is characterised by abnormal cellular metabolism and defects in organelles function, leading to impaired cardiac function. Read more

MSc by Research: Investigation of mitochondrial biology and neurodegeneration

Phosphorylation and ubiquitylation are reversible signalling events and there is significant interest in in their interplay in the regulation of normal biological processes and disruption in human diseases. Read more
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