We have 14 autophagy PhD Projects, Programmes & Scholarships

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autophagy PhD Projects, Programmes & Scholarships

We have 14 autophagy PhD Projects, Programmes & Scholarships

Understanding the physiological roles and pathological impacts of ER-Autophagy

Autophagy is a lysosomal degradation pathway that is activated upon stress to facilitate clearance of damaged/toxic intracellular contents and recycle essential building blocks to sustain cell survival. Read more

How does TRIM21 degrade diverse substrates from viruses to neurodegenerative aggregates?

TRIM21 is the cytosolic E3 ligase and antibody receptor responsible for intracellular antibody immunity. Unlike other ubiquitin ligases, TRIM21 doesn’t have a defined substrate but is directed towards its targets by antibodies. Read more

Elucidation of a new pathological mechanism for brittle bone disease

The incidence of the brittle bone disease osteogenesis imperfecta (OI) is estimated to be around 1 in 10,000 individuals. The phenotypic spectrum of OI ranges from mild to perinatal lethal and includes extra-skeletal connective tissue manifestations. Read more

MSc by Research: Understanding the functions of ERphagy via its targeted cargos

The selective degradation of the endoplasmic reticulum via autophagy, also known as ERphagy, is a fundamental cellular process that has been observed under different stresses and stimuli. Read more

LPS ubiquitylation and innate immunity

Our ability to fight infections relies not on the capacity of our professional immune system to defend our body but also on the skills of individual cells to defend themselves. Read more

Funded MRC PPU PhD Programme 2025, University of Dundee, Scotland

The MRC Protein Phosphorylation and Ubiquitylation Unit is a world-famous centre for the study of cell signaling and how disruption to signaling pathways causes human disease. Read more

Molecular mechanisms underlying Parkinson's disease

There is great need for improved understanding of the mechanistic biology underlying Parkinson’s disease. Such knowledge will help with development of new drugs that slow or even halt the progression of the disease. Read more

Intracellular Capillarity of Biomolecular Condensates

The emerging role of biomolecular condensates formed through a liquid-liquid phase separation process inside biological cells is driving a paradigm change in our understanding of cellular organisation. Read more
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