Differentiation of B lymphocytes in response to vaccination
Prof K Toellner
Applications accepted all year round
B lymphocytes upon contact by antigens undergo a complex programme of differentiation and migration through lymphoid microenvironments, before they differentiate into either plasma cells or convert into memory B cells.
Epigenetic mechanisms in CD5+ malignant B lymphocytes
Centre for Experimental Medicine
Dr E Kostareli, Prof K Mills
20 January 2019
B-cell receptor (BCR) signalling is a complex molecular network critical for normal B-cell development and function. Among the numerous proteins of BCR pathway, Bruton tyrosine kinase (BTK) has gained significant attention over the last decade.
Cryptosporidium parvum – B-cells as a route to control
Dr R Flynn
11 January 2019
Cryptosporidium parvum infection presents a major threat to calf health and survival as a global cause of enteric disease. Calves under the age of 2 months are 41 times more likely to shed oocysts in comparison with animals aged 4 months or above.