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bacterial proteins PhD Projects, Programmes & Scholarships
We have 23 bacterial proteins PhD Projects, Programmes & Scholarships
We have 23 bacterial proteins PhD Projects, Programmes & Scholarships
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Structure and function of bacterial proteins
In the current era of growing antibiotic resistance cases, the world needs new therapeutics against bacterial infections. The project will focus on the investigation of structure and function of selected bacterial proteins, which could lead to the development of new therapeutics. Read more
Engineering biosensors for the detection of bacterial proteins
Superbug outbreaks are more likely to occur in a healthcare environment and are causing an increasing number of deaths every year. Read more
Barrier functions of the sugary cell coat – Understanding how extracellular signalling proteins and bacterial toxins navigate the cell surface
Are you keen to progress research in glycoscience at the interface between biology, chemistry, and physics?. Glycocalyces are carbohydrate-rich coats surrounding virtually every cell in our body. Read more
Electromechanics in charge transport proteins
The outstanding ability of redox proteins to transport charge in exceedingly long length scales is still puzzling the scientific community. Read more
A new approach to CRISPR-Cas adaptation and the discovery of host accessory-proteins
Bacteria provide many health benefits and eco-environmental services. Although physically simple, they have a sophisticated immune system, CRISPR-Cas. Read more
Designing inhibitors of protein-protein interactions for bacterial cell division for specific antibiotics (BEEKMANA_U23SF)
Antibiotic-resistant pathogens are a huge threat in healthcare. The last resorts of conventional antibiotic drugs are unable to treat multi-resistant strains in patients. Read more
Nutritional immunity: the battle for iron between host and pathogen
The innate immune defence system responds to bacterial infection by reducing the amount of available iron to restrict bacterial growth. Read more
PhD Studentship in Computing: Comparative interactomics for synthetic bacterial systems
Overview. Interested in the intersection between systems biology and engineering biology? This PhD will explore the effect of synthetic manipulation on cellular systems. Read more
MycoTACs: Proteome targeting chimeras for Mycobacterium tuberculosis
PROteolysis Targeting Chimeras (PROTACs) are a promising and recent technological development utilised in the degradation of proteins in eukaryotes. Read more
Understanding the molecular mechanism of a novel innate bacterial defence system and its synergy with CRISPR-Cas
Prokaryotes have evolved over billions of years alongside their viruses, the bacteriophages, or “phages”. To prevent viral infection, prokaryotes have evolved rudimentary immune mechanisms, the most widespread and well‐studied of which are the Restriction‐Modification and the CRISPR‐Cas enzymes. Read more
Development of carbohydrate-functionalised materials for detection and prevention of medical device-associated infections
Antibiotic-resistant bacteria are a growing problem in the 21st century, causing longer and more serious infections, and resulting in poor outcomes for vulnerable patients. Read more
Combining protein modelling and synthetic biology to alter and expand of host range of phages
Phage therapy relies on the use of bacterial viruses for treatment of infectious diseases. Bacteriophages are natural predators of bacteria, but their specificity varies significantly depending on the host species. Read more
Protein disorder in chlamydia infection (BLUMENSCHEINT_U23SF)
Chlamydia is a bacterial obligate intracellular parasite which extensively modifies the host cell for its own advantage during infection. Read more
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Functional Analysis of Bacteroides fragilis Ubiquitin
Molecular mimicry by infectious agents is hypothesized to be a trigger for the development of autoimmunity. It is proposed that exposure of the immune system to exogenous molecules with a sufficiently similar structure either breaks tolerance to self-antigens or activates pre-existing but unreactive immune system cells. Read more
Elucidating the mechanisms of outer membrane biogenesis in Gram-negative bacteria
The emergence of bacteria that are resistant to available antibiotics represents an enormous and growing global threat requiring new targets and strategies to combat infection. Read more
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