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bacteriophage PhD Projects, Programmes & Scholarships

We have 12 bacteriophage PhD Projects, Programmes & Scholarships

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We have 12 bacteriophage PhD Projects, Programmes & Scholarships

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The development of bacteriophage as bionanoparticles for gene therapy

Gene therapy is at the forefront of innovations in healthcare. The key unmet need for transformative exploitation of gene therapy is to deliver genes to the correct tissue safely and with efficacy. Read more

EASTBIO Engineering the genome of bacteriophage T5

  Research Group: Biomedical Sciences Research Centre
Bacteriophage T5 is a model E. coli-infecting lytic phage with a 121 kb linear double-stranded DNA genome that is arranged into pre-early, early and late transcription units, encoding in total around 160 proteins and 20-25 tRNAs. Read more

Investigation of the effect of oxygen and temperature levels on E.coli K1 phages infection

  Research Group: Midlands Integrative Biosciences Training Partnership (MIBTP)
The problem of antimicrobial resistance is nowadays major and the need to identify alternative methods to antibiotics to tackle bacterial pathogens is obvious. Read more

Eastbio Developing bacteriophage technology to target foodborne Escherichia coli O157 in packed foods

The proposed project seeks to develop an innovative bacteriophage (phage, virus of bacteria) technology to control the Shiga-toxin producing Escherichia coli (STEC) O157 safely and effectively in food packaging to complement other control and surveillance strategies, and to save lives. Read more

EASTBIO Dissecting the role of the BRCT domain in bacterial DNA ligase activity - a novel target for antimicrobial action?

  Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology
DNA ligases play a critical role in DNA replication, repair and recombination in all living organisms, joining DNA ends whenever new DNA is made or when damaged DNA is repaired. Read more

MRC DiMeN Doctoral Training Partnership: Towards phage therapy: combining genetics and cutting edge CryoEM to optimise a superbug-killing virus

Increasing resistance to antibiotics is one of the greatest health challenges facing humanity today. Clostridioides difficile is the primary cause of antibiotic-associated infections in UK hospitals and antibiotic-induced disruption of the gut microbiota is a prerequisite for infection. Read more
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