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We have 9 bbb PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
bbb PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
We have 9 bbb PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships
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4 Year PhD with Integrated MSc in Neuroscience: ApoE-ε4 induced blood-brain barrier dysfunction in Alzheimer’s disease
Background. Blood-brain barrier dysfunction in Alzheimer’s Disease (AD). The blood-brain barrier (BBB) is formed by a continuous layer of cerebral endothelial cells held together by tight junction proteins (TJP), which restrict the movement of molecules. Read more
(EPSRC DTP) Developing MRI acquisition and modelling to measure water exchange processes in the brain
Magnetic resonance imaging (MRI) is a non-invasive imaging modality that can produce exquisite images of the brain. Read more
Analysing the factors that regulate expression of blood-brain barrier drug transporter proteins
In order to treat diseases associated with the central nervous system (CNS), e.g. cancer, Parkinson’s disease, depression, it is essential for therapeutic drugs to be able to penetrate into the brain. Read more
Synthesis of novel metal chelators against Parkinson’s Disease (ref: SF22/HLS/APP/TETARD)
The involvement of iron in the development of Parkinson’s Disease is now well recognised. Iron seems to be accumulating in the neurons of sufferers and is involved in the formation of reactive oxygen species that cause oxidative damage to neurons, resulting in their death. Read more
Delivery of THC derivatives across the BBB: functionalised polysaccharides nanocarriers
Cannabis sativa, commonly known as marijuana has been found to contain 525 natural components that fall under several chemical classes. Read more
PhD Scholarship to study blood-brain barrier dysfunction in atrial fibrillation
This is an excellent opportunity for a talented and motivated applicant to undertake an original programme of research working within the Brain Barriers Research Group (. Read more
Hybrid antioxidant nanocarriers for the treatment of Alzheimer’s disease
Alzheimer’s disease (AD) is a neurodegenerative disorder that yearly affects 50 million people worldwide, a number estimated to grow to 139 million in 2050. Read more
Peptide-based nanoparticles for brain targeted gene delivery
Gene therapy has the potential to provide therapeutic benefit to millions of people with neurodegenerative diseases and cancer. Delivery into the brain is hampered by the blood-brain barrier (BBB), which limits the efficacy of both conventional and novel therapies at the target site. Read more
Carbon nanotubes in the boron neutron capture therapy of cancer
The early promise of boron neutron capture therapy as a method for the treatment of brain cancer has been mainly inhibited by the inherent toxicity associated with 10B-containing pharmacophores and the need for the ability to cross biological membranes. Read more
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