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biomed PhD Projects, Programmes & Scholarships
We have 43 biomed PhD Projects, Programmes & Scholarships
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Identifying the neurobiological signatures of multisensory processing of emotional information to establish biomarkers for anxiety and posttraumatic stress disorder MRC GW4 BioMed DTP PhD studentship 2023/24 Entry- PhD in Maths and Statistics
Summary. Mathematical modelling and data analysis provide powerful tools to identify features of brain electrical activity along with other physiological signals. Read more
Quantitative analysis of Wnt signalling in the Gastric Tumour Microenvironment. MRC GW4 BioMed DTP PhD studentship 2023/24 Entry, PhD in Biosciences.
Summary. Gastric cancer is a multifactorial disease-causing over a million deaths yearly. Deregulation of oncogenic cell signalling, such as the Wnt signalling pathway, leads to tumour growth and metastasis. Read more
Modelling human embryo development: a combined mathematics and lab approach. MRC GW4 BioMed DTP PhD studentship 2023/24 Entry, PhD in Physics
Summary. During this PhD, you will use mathematics, computer programming and lab-based experiments to investigate how the human embryo develops, focusing on the very first few days after fertilisation when the embryo grows from a single egg to several hundred cells. Read more
Does microplastic exposure impact our health and cause immune dysfunction? MRC GW4 BioMed DTP PhD studentship
HOW TO APPLY. Deadline for applications. 5:00 pm on Wednesday, 2nd November 2022. For an overview of the MRC GW4 BioMed programme please see the website. Read more
Developing computational models of psychosis to explore the impact of schizophrenia-associated CNVs on cortical microcircuitry MRC GW4 BioMed DTP PhD studentship 2023/24 Entry- PhD in Psychology
Summary. Breakthroughs in genetics have identified specific CNVs that substantially increase risk for schizophrenia. These CNVs impact NMDA & GABAA receptors, but how this disrupts cortical function is unknown. Read more
Award details Exploiting lipid binding proteins to tackle neurological disorders. MRC GW4 BioMed DTP PhD studentship 2023/24 Entry- PhD in Biosciences
Summary. This multi-disciplinary project combines cutting-edge molecular cell biology, neurobiological, and biochemical (lipid analysis) approaches to reveal novel links between organelle membrane proteins, lipid metabolism, and neurodegenerative disorders. Read more
Statistical inference of cell type specific epigenetic profiles for the molecular epidemiology of brain disorders. MRC GW4 BioMed DTP PhD studentship 2023/24 Entry, PhD in Medical Studies
Summary. Genetic risk factors for brain disorders can have substantial impacts on the regulation of gene activity, but we only have a limited understanding of how this manifests across the different cell types of the brain. Read more
Functional assembly of 3D neuromuscular junctions on a chip for neuromotor disease modelling. MRC GW4 BioMed DTP PhD studentship 2023/24 Entry, PhD in Physics
Summary. The neuromuscular junction (NMJ) is an essential synapse for muscle contraction and movement. Understanding the functional establishment of an NMJ is crucial to studying neuromotor processes and associated diseases such as ALS. Read more
Mapping pathogen transport and retention near ciliated surfaces. MRC GW4 BioMed DTP PhD studentship 2023/24 Entry, PhD in Mathematics
Summary. Cilia fulfil numerous physiological functions. From protists to mammals, cilia have highly conserved structure and function. Read more
The role of prenatal inflammation on neurodevelopmental disorders MRC GW4 BioMed DTP PhD studentship 2023/24 Entry- PhD in Psychology
Summary. Inflammation during pregnancy as a result of stress and infection is linked could increase the risk of autism and attention-deficit hyperactivity disorder in the child, potentially by influencing their brain development. Read more
Developing novel microfluidic platforms for antibiotic discovery. MRC GW4 BioMed DTP PhD studentship 2023/24 Entry, PhD in Biosciences
Summary. Antimicrobial resistance is one of the most pressing public health challenges and threatens the ability to effectively fight infectious diseases, with around 10 million people predicted to die annually of infections by 2050. Read more
Pharmacological targeting of AMP-activated protein kinase for immune cell regulation in Type 1 Diabetes. MRC GW4 BioMed DTP PhD studentship 2023/24 Entry, PhD in Medical Studies.
Summary. The ambition of this project is to discover new approaches to dampen the immune-mediated attack on the pancreatic beta cell seen in type-1diabetes. Read more
Investigating the role of DNA methylation in C9ORF72 Amyotrophic Lateral Sclerosis. MRC GW4 BioMed DTP PhD studentship 2023/24 Entry, PhD in Medical Studies.
Summary. During this PhD you will use innovative molecular techniques to investigate a repeat expansion in the C9ORF72 gene, the most common genetic cause of Amyotrophic lateral sclerosis (ALS). Read more
Investigating neural fine-tuning of pancreatic islet activity in glucose homeostasis and diabetes prevention MRC GW4 BioMed DTP PhD studentship 2023/24 Entry- PhD in Medical Sciences
Summary. Hormone release from pancreatic islets (insulin from beta cells & glucagon from alpha cells) is tightly coordinated. This coordination is critical for glucose homeostasis and its loss leads to diabetes. Read more
Integrative analysis of whole genomes and transcriptomes from multiple cell types in rare disease patients. MRC GW4 BioMed DTP PhD studentship 2023/24 Entry-PhD in Medical Sciences
Summary. The use of Whole-Genome Sequencing has increased the diagnostic yield for rare diseases. However, even WGS fails to identify the genetic cause in about 50% of patients. Read more
