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biosynthesis PhD Projects, Programs & Scholarships

We have 32 biosynthesis PhD Projects, Programs & Scholarships

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  PhD in the Biosynthesis and Enzymology of Fluorine Containing Metabolites in Streptomyces Bacteria
University of St Andrews School of Chemistry
  Prof D O'Hagan
Applications accepted all year round
Research in the O’Hagan group has had a focus on the biosynthesis of fluorine containing natural products and the identification of a fluorination enzyme, ‘the fluorinase’, from Streptomyces cattleya.[1] Fluorine is very rare in nature, and in those rare cases where an organism can form a C-F bond from fluoride ion, then the enzymology is unique and interesting.
Details
Type/Funding
  Condition specific engineering of P. putida for rhamnolipid production
University of Portsmouth Centre for Enzyme Innovation
  Dr P Rahman, Dr S Robson, Dr C Angione
Application Deadline: 24 February 2019
Applications are invited for a competition-funded three year PhD studentship to commence in October 2019. The project will focus on.
Details
Type/Funding
  Structure, Function and Biogenesis of the Mycobacterial Cell Wall
University of Birmingham School of Biosciences
  Prof G Besra
Applications accepted all year round
There has been no significant decrease in worldwide mortality due to tuberculosis (TB) since before the time of Koch; the advent of sanatoria and chemotherapy, which drastically reduced TB in the more developed countries, has had no profound effect on the global problem.
Details
Type/Funding
  A hidden biochemical pathway in the chemical pathology of diabetes (HAMILTONCU19SF)
University of East Anglia School of Pharmacy
  Dr C Hamilton
Applications accepted all year round
In humans, the cysteine-containing tripeptide glutathione (GSH) is an essential thiol cofactor that maintains an intracellular reducing environment to protect against oxidative stress reactive oxygen species, which cause lipid, protein & DNA damage.
Details
Type/Funding
  (BBSRC DTP) Novel antimicrobial discovery using high-throughput pathway assembly and robotics
University of Manchester School of Chemistry
  Prof E Takano, Prof A Munro, Prof R Breitling
Application Deadline: 31 January 2019
This is an interdisciplinary research project in Industrial Biotechnology, especially in the emerging area of Synthetic Biology applied to antimicrobial resistance.
Details
Type/Funding
  MRC DiMeN Doctoral Training Partnership: Understanding the molecular pathophysiology of stress on the developing and adult brain
University of Sheffield MRC DiMeN Doctoral Training Partnership
  Dr N Krone, Dr V T Cunliffe
Application Deadline: 21 January 2019
Stress is associated with significant morbidity including depression and anxiety. Activation of the hypothalamic-pituitary-adrenal (HPA) axis leads to synthesis of cortisol, which is a key mediator of the pathology of chronic stress.
Details
Type/Funding
  Peptidomimetic Inhibitors for the MraY-protein E interaction site as anti-Pseudomonas therapeutics
University of Warwick Warwick Medical School
  Prof T Bugg
Application Deadline: 14 February 2019
PhD in Interdisciplinary Biomedical Research. Fully funded studentship available for entry in September 2019. This Industrial Collaborative Award in Science and Engineering (iCASE) studentship is offered by Warwick’s MRC Funded Doctoral Training Partnership (DTP).
Details
Type/Funding
  Developing computational models for engineering glycosylation of biologics
University of York Department of Biology
  Dr D Ungar, Dr A J Wood, Prof J E Thomas-Oates
Application Deadline: 21 January 2019
Biologics are the most rapidly growing class of pharmaceuticals, with over 50% of the highest earning blockbuster drugs falling into this category.
Details
Type/Funding
  Antibody engineering to identify optimal expression systems and glycoforms of IgE class antibodies for cancer therapy
King’s College London Health Schools
  Dr S Karagiannis, Dr G Wagner
Application Deadline: 1 March 2019
Fully funded 4-year PhD Studentship with the MRC Doctoral Training Partnership at King’s College London. Applications Open. Friday 18th January.
Details
Type/Funding
  Structural and functional analysis of cytokinin-regulated DIRIGENT proteins from Arabidopsis thaliana
Masaryk University CEITEC
  Dr B Pekarova, Prof J Hejátko
Application Deadline: 15 March 2019
Our Research Group Functional Genomics and Proteomics of Plants has been investigating plant hormonal signaling pathways, particularly cytokinins and ethylene in the development of model plant Arabidopsis thaliana (1-4) for a long time.
Details
Type/Funding
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