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brain cancer PhD Projects, Programs & Scholarships

We have 36 brain cancer PhD Projects, Programs & Scholarships

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  Non coding RNAs in Adrenocortical Cancer
  Prof G. Hutvagner
Applications accepted all year round

Funding Type

PhD Type

Background. Industry, society or clinical need for project and scientific rationale. Adrenocortical carcinoma (ACC) is a rare disease which occurs with an annual incidence of 2-4 cases per million with a five-year survival of less than 16-38%.
  Cellular cross-talk at the perivascular niche and the blood brain barrier
  Prof B Hogan
Applications accepted all year round

Funding Type

PhD Type

Much research on vasculature has focussed on the endothelial cells that line functional vessels, however the milieu of cells that surround vessels (mural cells) play important and under-appreciated roles in homeostasis and disease.
  RET a novel therapeutic target to treat breast cancer brain metastasis
  Prof L Young, Dr A Hill
Applications accepted all year round

Funding Type

PhD Type

Metastatic disease recurrence occurs in up to 30% of breast cancer patients with approximately 20% of these tumours metastasising to the brain.
  The Hippo pathway and Yap1 in vascular growth control in development and disease
  Prof B Hogan, Dr A. Cox
Applications accepted all year round

Funding Type

PhD Type

Lymphatic vessels play roles in the drainage of tissue fluid, trafficking of immune cells and the metastatic spread of cancer.
  How does amino acid metabolism affect tumour growth?
  Dr L. Cheng
Applications accepted all year round

Funding Type

PhD Type

The effect of diet on tumour growth is hotly debated but poorly characterized. Due to the heterogeneous nature of the tumours, dietary studies in patients with varied genetic background often led to inconclusive outcome.
  Carbon nanotubes in the boron neutron capture therapy of cancer
  Dr G Calabrese
Applications accepted all year round

Funding Type

PhD Type

The early promise of boron neutron capture therapy as a method for the treatment of brain cancer has been mainly inhibited by the inherent toxicity associated with 10B-containing pharmacophores and the need for the ability to cross biological membranes.
  Mechanisms of Cancer Stem Cell Survival, Metastasis Formation and Immune Evasion in Cancer
  Dr D Widera
Applications accepted all year round

Funding Type

PhD Type

Recent research suggests that cancer cells within a tumour represent a highly heterogeneous cell population. In particular many tumours contain small percentage of cells that share several characteristics with stem cells.
  Glioblastoma: A Nanotechnology Approach for Glioblastoma Targeted Therapy
  Research Group: Medical Engineering
  Dr F Sefat, Dr M Najafzadeh
Applications accepted all year round

Funding Type

PhD Type

Glioblastoma is a type of brain cancer. It’s the most common type of malignant brain tumor among adults and it is usually very aggressive, which means it can grow fast and spread quickly.
  Analysing the factors that regulate expression of blood-brain barrier drug transporter proteins
  Dr J L Penny, Dr C Demonacos
Applications accepted all year round

Funding Type

PhD Type

In order to treat diseases associated with the central nervous system (CNS), e.g. cancer, Parkinson’s disease, depression, it is essential for therapeutic drugs to be able to penetrate into the brain.
  Imaging the local accumulation and clearance of protein aggregates in the extracellular space of the brain in Alzheimer’s disease models.
  Research Group: Biomedical Sciences Research Centre
  Dr J Varela, Prof F Gunn-Moore
Application Deadline: 15 June 2020

Funding Type

PhD Type

Small aggregates of misfolded proteins are thought to be the main cause for cellular death in a wide variety of neurodegenerative diseases.
  Neuronal Src kinases: oncogenes in brain development?
  Dr G Evans, Dr S Chawla
Application Deadline: 30 June 2020

Funding Type

PhD Type

The challenges of the developing human brain include co-ordinating the birth and migration of 100 billion neurons and the formation of their 1000 trillion synaptic connections.
  Role of the microbiome in neurodegenerative disease
  Prof J Ketley, Prof F Giorgini
Application Deadline: 7 June 2020

Funding Type

PhD Type

The human microbiome is essential for human health as it is crucial for the development of immunity, tissue development, host metabolism and protection from various infectious diseases.
  Nanotechnologies for cancer: developing new polymer-drug conjugates for the treatment of a range of cancers
  Dr F Greco, Prof H Osborn
Applications accepted all year round

Funding Type

PhD Type

Polymer anticancer-drug conjugates are drug delivery systems in which a low molecular weight anticancer agent is covalently conjugated to a water-soluble polymeric carrier.
  TARGETING MITOPHAGY TO REDUCE CHEMOTHERAPY-INDUCED PAIN
  Dr M Maiaru
Applications accepted all year round

Funding Type

PhD Type

"Background. Chemotherapy-induced peripheral neuropathy (CIPN) is the most commonly reported side effect of chemotherapeutic drugs, affecting quality of life in many cancer patients.
  Understanding microtubule-actin crosstalk in neuronal cell migration
  Prof A M Fry, Prof I D Forsythe
Application Deadline: 7 June 2020

Funding Type

PhD Type

Summary. This BBSRC-funded 4-year PhD studentship will address the mechanism of action of a microtubule-associated protein, EML4, in promoting microtubule-actin crosstalk and neuronal cell migration [1].
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