Chemical modulation of cellular redox balance for cancer treatment
Dr I Romero-Canelon
Applications accepted all year round
Platinum complexes, cisplatin, oxaliplatin and carboplatin, are the most widely used anticancer drugs. However, these DNA-targeting treatments are a low selectivity approach with deleterious consequences and a high incidence of resistance.
Understanding and targetting telomere maintenance in cancer
Dr D Clynes, Dr A Blackford, Dr R Gibbons
11 January 2019
Cancer occurs through the uncontrolled growth and division of cells, which eventually leads to the development of a tumour. The number of times a cell can divide is limited by the length of specialised DNA sequences found at the end of chromosomes.