Our group has a track record of identifying novel colorectal cancer (CRC) predisposition genes and translating these findings into clinical practice (Al-Tassan et al. Read more
All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more
All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more
This project is one of 15 four year PhD Studentships funded by Medical Research Scotland (MRS) (. https://www.medicalresearchscotland.org.uk. Read more
We are seeking a highly motivated student, preferably with knowledge of the following areas. bioinformatics, genetics/epigenetics, machine-learning and/or statistical modeling. Read more
Several post graduate research (PGR) studentships (MD/MPhil/PhD) are available in the Division of Cancer and Genetics (DCG), Cardiff University School of Medicine to start in 2023. Read more
Overview. This project will explore the role of transport proteins in Breast Cancer (BC), focusing on the solute carrier (SLC) superfamily (incorporating the SLCO and the SLC22A families), which mediate solute uptake into cells, and the ABC family, which mediates efflux out of cells. Read more
Background. Accumulating research suggests that a disturbance in the gut microbiome can influence development of colorectal neoplasia from early lesions to tumours (1). Read more
This opportunity will remain open until a suitable candidate has been found and so early applications are encouraged. Cancer-associated changes in gene expression and genome stability are often attributed to variations in DNA methylation. Read more
Applications are invited for a three-year PhD studentship available at Dr Claudia Barros’ group, Peninsula Medical School, University of Plymouth, UK. Read more
DNA-protein crosslinks (DPCs) are under-investigated DNA lesions caused by the covalent attachment of proteins to DNA. DPCs are induced by endogenous aldehydes, chemotherapeutic drugs (such as PARP1 or Topoisomerase inhibitors) and ionising radiation. Read more
Prostaglandin E2 (PGE2) is a small lipid molecule frequently elevated during inflammation and cancer through increased synthesis by cyclo-oxygenase 2 (COX-2). Read more
In multi-cellular organisms, coordinated cell death (e.g. apoptosis) and cell replacement is critical for tissue recovery in response to stress or damage. Read more
The major aim of this project is to assist in the validation of induced protein degradation as a viable strategy to develop novel anti-cancer therapies. Read more
*Offer only available for the duration of your active subscription, and subject to change. You MUST claim your prize within 72 hours, if not we will redraw.
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