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cancer stem cells PhD Projects, Programs & Scholarships

We have 41 cancer stem cells PhD Projects, Programs & Scholarships

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  Aldehyde dehydrogenase expression and function in cancer stem cells
  Research Group: Institute of Cancer Therapeutics
  Dr K Pors, Dr A Mardaryev, Prof A Locke
Applications accepted all year round
Aldehyde dehydrogenases (ALDHs) catalyse the oxidation and detoxification of reactive endogenous and exogenous aldehydes into carboxylic acids via NAD+ coupled reduction.
  How does amino acid metabolism affect tumour growth?
  Dr L. Cheng
Applications accepted all year round
The effect of diet on tumour growth is hotly debated but poorly characterized. Due to the heterogeneous nature of the tumours, dietary studies in patients with varied genetic background often led to inconclusive outcome.
  Ran GTPase as a potential novel therapeutic target in EMT transdifferentiation and breast cancer stem cell (BCSC) survival during metastatic development
  Research Group: Institute of Cancer Therapeutics
  Prof R Morgan, Prof M El-Tanani, Dr M Isreb, Dr M Najafzadeh
Applications accepted all year round
Breast cancer is the leading cause of cancer death in women worldwide. Accumulating evidence suggests that local disease recurrence and metastatic lesions, the major causes of patient mortality, are due to a subset of aggressive cells termed cancer stem cells (CSCs).
  Therapy-induced senescence and stemness in ovarian cancer
  Prof R. Pearson, Dr K Chan
Applications accepted all year round
Cellular senescence is a stress response characterized by a robust cell cycle arrest and is a brake for malignant transformation.
  Mechanisms of Cancer Stem Cell Survival, Metastasis Formation and Immune Evasion in Cancer
  Dr D Widera
Applications accepted all year round
Recent research suggests that cancer cells within a tumour represent a highly heterogeneous cell population. In particular many tumours contain small percentage of cells that share several characteristics with stem cells.
  Characterizing the heterogeneity of stem cells in the normal breast and breast tumours
  Dr A Ucar, Prof K R Brennan
Applications accepted all year round
Tissue-restricted stem cells are crucial in supporting the development and maintenance of normal tissues. This is also true for tumours, as only a small population of tumour cells, which are known as cancer stem cells, have the unique stemness features and tumour-initiating capacity.
  4 Year Wellcome Trust PhD Programme: Mechanisms of asymmetric stem cell division
  Dr J Januschke
Application Deadline: 8 April 2019
Despite tremendous progress the origin of cancer is still a matter of debate for many malignancies, but it is clear that stem cells play an important part in this context.
  The development of new metallopharmaceuticals to target tumour subpopulations
  Dr K Suntharalingam
Application Deadline: 25 April 2019
3.5 Year PhD Studentship available for September 2019. Department. Chemistry. Supervisors. Dr Kogularamanan Suntharalingam. Eligibility.
  Characterizing the in vivo functions of P-Rex1 in breast development and tumourigenesis
  Dr A Ucar, Prof K R Brennan, Dr A Malliri
Applications accepted all year round
Breast cancer is the most common cancer in the UK with a lifetime risk of 1-in-8 for women and accounts for 12,000 deaths annually.
  Exploring Stem Cell Regulation by Heparan Sulphates using Chemical Biology and Glycomics Strategies
  Prof J E Turnbull
Applications accepted all year round
Heparan sulphates (HS) are complex sulphated polysaccharides expressed at the cell surface. They are essential co-receptors for many proteins, most notably many signalling growth factors, and they act as dynamic regulators of protein function.
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