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cancer stem cells PhD Projects, Programmes & Scholarships

We have 63 cancer stem cells PhD Projects, Programmes & Scholarships

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We have 63 cancer stem cells PhD Projects, Programmes & Scholarships

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Prostate cancer signalling to the bone micro-environment - from molecular characterization to potential novel therapies.

About the Project. Prostate cancer is responsible for over 52,000 cancer diagnoses within the UK per annum, and is the most common cancer in males, accounting for 27% of all new cancer cases diagnosed within men in 2016-2017. Read more

Mechanisms of Cancer Stem Cell Survival, Metastasis Formation and Immune Evasion in Cancer

Recent research suggests that cancer cells within a tumour represent a highly heterogeneous cell population. In particular many tumours contain small percentage of cells that share several characteristics with stem cells. Read more

Nanoparticles for targeting stem cells

Stem Cells play intriguing roles in different approaches to therapy. In regenerative medicine, injected stem cell-based therapies have emerged as a key approach, while in cancer treatment cancer stem cells are believed to act as a reservoir of new resistant tumour cells, responsible for post-treatment tumour relapses. Read more

Single-Cell Lineage Mapping of Elite CAR-NK Cells

The advance of chimeric antigen receptor (CAR) technology has been a breakthrough in cancer immunotherapy. However, it is not clear in which subpopulation of immune cells the endowment of CAR will be most effective in treating cancer. Read more

Cancer: Epigenetic therapy using microbubble-mediated drug delivery for colorectal cancer

The project is an interdisciplinary, pre-clinical study that aims to investigate the response of human tumour cells to treatment with epigenetic inhibitors (including DNA methyltransferase inhibitors, HDAC inhibitors and/or vitamin C), as a potential combination therapy for colorectal cancer (CRC). Read more

Investigation of prostate cancer stem cell targeting therapeutics with clinical potential

  Research Group: Institute of Cancer Therapeutics
Prostate cancer (PCa) patients with aggressive disease are associated with. Aim. To evaluate ALDH-targeting therapeutics as a new strategy to treat prostate cancer stem cells. Read more

Exploring the role of MYBL2 in Replication stress

Every time a cell divides, the genome must be faithfully duplicated and segregated to provide a copy for each daughter cells. The complexity of DNA processing in combination with the persistent exposure to genotoxic stimuli means that the fidelity of the genetic code is constantly under threat. Read more

The role of long non-coding RNA regulatory networks in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with a 5-year survival rate of approximately 11%. This is mainly due to late detection, early metastasis and resistance to treatments. Read more

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