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cardiac physiology PhD Projects, Programmes & Scholarships
We have 10 cardiac physiology PhD Projects, Programmes & Scholarships
We have 10 cardiac physiology PhD Projects, Programmes & Scholarships
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Non-invasive cardiac metabolism assessment using ultra-high field (7T) MR Spectroscopy
My group at the Oxford Centre for Clinical Magnetic Resonance Research (OCMR) is focused on development of new methods for cardiac metabolism assessment using magnetic resonance spectroscopy (MRS). Read more
Uncovering anti-arrhythmic potential of stellate ganglion purinergic receptors.
Background. Cardiovascular disease affects over 30% of people worldwide, and is one of the leading causes of death each year. Elevated sympathetic nerve activity is a common feature of cardiovascular disease, contributing to end-organ damage, morbidity and mortality [1-3]. Read more
Runx1 and Heart Failure
Project outline: . Coronary heart disease (CHD) leading to myocardial ischaemia is the predominant cause of heart failure (HF) and premature mortality in the UK. Read more
Mechanistic understanding of cancer drug induced cardiotoxicity using patient derived induced pluripotent stem cell (iPSC) derived cardiomyocytes
Background. Cardiovascular disease is the number one non-cancer cause of death in cancer survivors, attributable to side-effects of cancer medications routinely given to patients. Read more
Modulation of the Hippo signalling pathway to enhance cardiac regenerative capacity
Common heart diseases such as heart failure (HF) and coronary heart disease (CHD) are characterized by cardiomyocyte loss due to necrosis and apoptosis. Read more
Understanding why cardiovascular dysfunction is one of the leading causes of mortality in patients with Non-Alcoholic Fatty Liver disease (NAFLD)
Background. Liver disease accounts for 3.5% of all global deaths/year (~2 million people) and is the third leading cause of premature death in the UK with some of the highest hospitalisations in the country seen in areas of socioeconomic deprivation. Read more
Imaging in Preventive Cardiology Research
The Preventive Cardiology Research Group aims to improve how we identify and prevent heart disease in young people. There is a particular interest in links between pregnancy complications such as preeclampsia and later cardiovascular disease in both the mother and child. Read more
Exercise and non-invasive brain stimulation on brain function, food cravings, and energy intake
Unhealthy dietary choice is one of the major causes of obesity, cardiovascular disease (CVD), and Type 2 diabetes (T2D). Despite evidence suggesting that a healthy diet reduces the risk of obesity, CVD and T2D, the impulse to consume highly palatable foods is difficult to be inhibited. Read more
Determining the roles that GRK and arrestin proteins play in the development of hypertension and vascular disease
G protein-coupled receptors (GPCRs) constitute a very large family of heptahelical, integral membrane proteins that mediate a wide variety of physiological processes ranging from the transmission of light and odorant signals to the mediation of neurotransmission and hormonal actions. Read more
Investigation of aortic remodelling in obesity and role of mitochondrial dysfunction
Obesity is a global healthcare and economic burden with currently more than 650 million adults classified as obese (WHO, 2017). Obesity is a common precursor to type 2 diabetes (T2DM), and both are risk factors for developing cardiovascular disease. Read more
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