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We have 798 cell PhD Projects, Programmes & Scholarships

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cell PhD Projects, Programmes & Scholarships

We have 798 cell PhD Projects, Programmes & Scholarships

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Understanding apoptotic heterogeneity in cell populations

Apoptosis is a form of programmed cell death that occurs in response to stress such as genomic damage. The decision to initiate apoptosis is taken at the outer mitochondrial membrane (OMM) by members of the Bcl-2 family of proteins. Read more

How one archaeal cell becomes two

The origin of eukaryotic cell organisation remains one of the great unknowns in the history of life on earth. However, there is growing consensus that eukaryotes likely arose from a merger between an Asgard archaeal cell and an alpha-proteobacterial cell over a billion years ago. Read more

Machine learning and statistical modelling of trans-omic networks in controlling cell identity, cell-fate decisions, and cancers

The advances in mass spectrometry-based proteomics and phosphoproteomics, and next-generation sequencing-based transcriptomics and epigenomics create the opportunity to study cell identity, cell-fate decisions, and complex diseases such as cancers at a system level. Read more

Investigation of antagonism of multiple RGD-binding integrins as a therapeutic strategy in advanced head and neck cancer

  Research Group: Institute of Cancer Therapeutics
Background. The integrins are a family of transmembrane receptors which mediate cell-cell and cell-ECM adhesion, and signalling across the cell membrane involved in pathways controlling cell migration, proliferation, differentiation, cell survival and apoptosis. Read more

Cancer: Inhibiting cell metabolism to enhance tumour cell death

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more

The functions of the YAP/TAZ oncoproteins in cell cycle control and tumour progression.

Background. Squamous cell carcinomas (SCCs) - cancers arising from multi-layered epithelia such as the skin epidermis or the oral mucosa - are the most diagnosed cancers in the UK and world-wide. Read more

PhD in Infection, Immunity, Antimicrobial Resistance & Repair - Understanding the interactions of Dengue virus with the immune system and its impact on disease

SUMMARY. Natural killer (NK) cells are critical for killing virus-infected cells but can also cause immunopathology. This project investigates whether Dengue virus manipulates NK ligands to prevent NK cell killing and whether NK cells contribute to dengue pathogenesis. Read more

Investigating the communication between cancer cells and cells in the tumour microenvironment to improve our understanding of epigenetic regulatory mechanisms and identify new targets for cancer therapy

It is well-established that the molecular mechanisms controlling gene expression are disrupted in cancer cells and work in this area has laid the foundations for targeted cancer therapies. We are interested in the regulatory pathways that control cell proliferation and cell migration and the events that disrupt this control in multiple types of cancer. Read more

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