Background. Squamous cell carcinomas (SCCs) - cancers arising from multi-layered epithelia such as the skin epidermis or the oral mucosa - are the most diagnosed cancers in the UK and world-wide. Read more
One of the key processes in embryo development is somitogenesis. This is the formation of segments, known as somites, that go on to develop into bone and skeletal muscle. Read more
Notch is one of the major highly conserved signalling pathways that regulate cell-cell communication which involves gene regulation mechanisms that control multiple processes during development and adult life, including cell fate specification within progenitors. Read more
About 1200 people a year are left paralysed in the UK due to a Spinal Cord Injury (or SCI). This is because injuries involving the central nervous system (CNS) have very poor capacities to regenerate, thus resulting in a permanent loss of function. Read more
The School of Molecular & Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2023/24. Read more
Our laboratory aims to understand how mutation in tumour suppressors and oncogenes causes cancer. We focus on understanding the biochemical basis of oncogene and tumour suppressor activity in order to develop new cancer therapies. Read more
T lymphocytes mediate long-term adaptive immunity to viruses and tumour cells. T lymphocytes recognize foreign antigens via specific interactions with the T cell receptor (TCR) that is expressed on the cell surface. Read more
Emerging evidence suggests that the therapeutic effect of radiotherapy is at least partly dependent upon the induction of an anti-tumour immune response. Read more
The choice of which genes are expressed and which are shut down underpins cell identity and differentiation, and the stable inheritance of such choices through cell division is relevant to aging, neurodegeneration and cancer. Read more
About 1200 people a year are left paralysed in the UK due to a Spinal Cord Injury (or SCI). This is because injuries involving the central nervous system (CNS) have poor capacity to repair or regenerate. Read more
The origin of eukaryotic cell organisation remains one of the great unknowns in the history of life on earth. However, there is growing consensus that eukaryotes likely arose from a merger between an Asgard archaeal cell and an alpha-proteobacterial cell over a billion years ago. Read more
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