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cell cycle PhD Projects, Programmes & Scholarships
We have 33 cell cycle PhD Projects, Programmes & Scholarships
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The functions of the YAP/TAZ oncoproteins in cell cycle control and tumour progression.
Background. Squamous cell carcinomas (SCCs) - cancers arising from multi-layered epithelia such as the skin epidermis or the oral mucosa - are the most diagnosed cancers in the UK and world-wide. Read more
MSc by Research: Investigation of the interplay between the cell cycle and Notch intracellular domain levels in presomitic mesoderm cells in somitogenesis
One of the key processes in embryo development is somitogenesis. This is the formation of segments, known as somites, that go on to develop into bone and skeletal muscle. Read more
MSc by Research: Does CDK1 regulate NICD turnover in a cell cycle dependant manner in Drosophila Melanogaster?
Notch is one of the major highly conserved signalling pathways that regulate cell-cell communication which involves gene regulation mechanisms that control multiple processes during development and adult life, including cell fate specification within progenitors. Read more
Uncovering the molecular mechanisms underlying spinal cord regeneration
About 1200 people a year are left paralysed in the UK due to a Spinal Cord Injury (or SCI). This is because injuries involving the central nervous system (CNS) have very poor capacities to regenerate, thus resulting in a permanent loss of function. Read more
Proteomic analyses of adhesion signalling in cancer
Why adhesion? Cell surface adhesion receptors play key roles in the control of cell movement, survival, division and differentiation. Read more
Live cell imaging of epithelial cancer cell proliferation for therapy
The School of Molecular & Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2023/24. Read more
Developing a novel cancer vaccine for low mutation burden tumours derived from the non-coding genome
Our laboratory aims to understand how mutation in tumour suppressors and oncogenes causes cancer. We focus on understanding the biochemical basis of oncogene and tumour suppressor activity in order to develop new cancer therapies. Read more
MSc by Research: Using genome editing to study the mechanisms of immune cell proliferation and differentiation
T lymphocytes mediate long-term adaptive immunity to viruses and tumour cells. T lymphocytes recognize foreign antigens via specific interactions with the T cell receptor (TCR) that is expressed on the cell surface. Read more
Interaction between DNA Polymerase theta inhibition and cGAS/STING activation
Emerging evidence suggests that the therapeutic effect of radiotherapy is at least partly dependent upon the induction of an anti-tumour immune response. Read more
White Rose BBSRC DTP: Structure and function of CIZ1-histone complexes
The choice of which genes are expressed and which are shut down underpins cell identity and differentiation, and the stable inheritance of such choices through cell division is relevant to aging, neurodegeneration and cancer. Read more
Fully-funded White Rose BBSRC DTP Biology Project: Structure and function of CIZ1-histone complexes
Lead supervisor. Prof Dawn Coverley. Co-supervisors. Prof Fred Antson. The student will be registered with the Department of Biology. Read more
PI3K-Akt expression in dysplastic oral lesions and implications for recurrence and malignant transformation
There are around 12,400 new head and neck cancer cases in the UK every year, that's 34 every day (2016-2018) with 4,143 deaths each year. Read more
Dynamics of neurogenesis during spinal cord regeneration
About 1200 people a year are left paralysed in the UK due to a Spinal Cord Injury (or SCI). This is because injuries involving the central nervous system (CNS) have poor capacity to repair or regenerate. Read more
How one archaeal cell becomes two
The origin of eukaryotic cell organisation remains one of the great unknowns in the history of life on earth. However, there is growing consensus that eukaryotes likely arose from a merger between an Asgard archaeal cell and an alpha-proteobacterial cell over a billion years ago. Read more
Last chance to apply
Characterising the mode of action of a novel anti-AT1R antibody (ATN-E11) on the proliferation, migration and angiogenesis in a range of cancer cell lines
Fixed term contract for 3 years, commencing January 2024. Bursary of £18,622 per annum and a full fee-waiver for UK tuition fees. Read more
