EML4 is a poorly characterised microtubule-associated protein . The purpose of this cell biology-focused PhD project is to explore the molecular mechanisms through which EML4 regulates microtubule dynamics and cell migration.
This 4-year PhD studentship is offered in Dr Michael Way’s Group based at the Francis Crick Institute (the Crick). Viruses are obligate intracellular parasites that critically depend on their hosts to generate new progeny.
Cancer is a devastating disease. more than one in three people in the UK will develop cancer in their lifetime. WNT signalling is a key pathway controlling morphogenesis in embryos and it has been shown that perturbations of this pathway promote cancer progression.
Collective cell migration – a process in which cohorts of cells move as a group while maintaining their mutual connections with each cell coordinating its movement with its neighbours – is a fundamental process in development and tissue regeneration.