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cell migration PhD Projects, Programmes & Scholarships

We have 82 cell migration PhD Projects, Programmes & Scholarships

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We have 82 cell migration PhD Projects, Programmes & Scholarships

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Understanding mechanisms driving tissue morphogenesis and cell fate during early embryonic development

  Research Group: Midlands Integrative Biosciences Training Partnership (MIBTP)
Background and scientific rationale. Embryonic tissues and organs are shaped and patterned by complex genetic, molecular and cellular mechanisms that regulate essential processes during development [1]. Read more

Cancer biology: identification of new treatment options for EML4-ALK driven lung cancer through understanding mechanisms of cell division and migration.

Lung cancer is the largest cause of cancer-related deaths in the UK and worldwide. While little progress has been made in long-term survival rates, we now have a good understanding of the genetic drivers raising the prospect of earlier diagnosis and more effective treatments. Read more

Significance of cytoskeletal filaments coordination in immunity and cell migration

The cytoskeletal organisation is fundamental for all cellular events, which defines the shape of the cells, the transport of molecules in different cellular domains, and controls the dynamics of cellular function. Read more

Is there a Role for Activated Akt in Palatogenesis?

Main Aim. The project will use a medial edge epithelial (MEE) cell line as an in vitro model. These cells will be used to investigate the effects of exogenous TGFβ-3 and activation of Akt on cell migration, epithelial to mesenchymal transition (EMT) and apoptosis. Read more

Investigation of antagonism of multiple RGD-binding integrins as a therapeutic strategy in advanced head and neck cancer

  Research Group: Institute of Cancer Therapeutics
Background. The integrins are a family of transmembrane receptors which mediate cell-cell and cell-ECM adhesion, and signalling across the cell membrane involved in pathways controlling cell migration, proliferation, differentiation, cell survival and apoptosis. Read more

Interactions between dietary isothiocyanates and anti-cancer drug sorafenib in breast cancer (BAOY_U23MED204350)

High consumption of cruciferous vegetables can reduce the risk of cancer. The protection has been attributed to high level of glucosinolates and their breakdown products isothiocyanates (ITCs) in cruciferous vegetables. Read more

Meals for macrophages – investigating how macrophages engulf and process dying cells in vivo

Supervisors. Iwan Evans (primary supervisor); Phil Elks and Simon Johnston (secondary supervisors). Project details. A critical role for phagocytic cells such as macrophages is the engulfment and subsequent degradation of dying cells and debris. Read more
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A correlative bioimaging, force and multiomics platform for skin cell mechanosensing: identification of new responsive proteins and the effects of aging.

The programme is a novel interdisciplinary mechanobiology research project, including training on world-class bioimaging instruments, where the student will learn further in-demand skills in experimental and computational transcriptomics and proteomics. Read more

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