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We have 166 cell signalling PhD Projects, Programmes & Scholarships
cell signalling PhD Projects, Programmes & Scholarships
We have 166 cell signalling PhD Projects, Programmes & Scholarships
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Biological role of neuropeptides and their receptors
Cell signalling is critical to the co-ordination and functioning of all cells. Cell signalling allows cells to co-ordinate activities within the intracellular environment as well as ensuring cells know how to correctly respond to other cells and to an ever-changing extracellular environment as well. Read more
Cell signalling and gene expression dynamics in Drosophila
During Drosophila development, cell signalling and gene expression are regulated in space and time to allow the correct cell fate decisions. Read more
Bifunctional small molecules beyond PROTACs: Proximity-inducing new downstream chemistries to rewire cell signalling
Proteolysis targeting chimeras (PROTACs) are a popular class of bifunctional molecules that simultaneously engage a target protein on one end and an E3 ubiquitin ligase on the other end, forming a ternary complex that facilitates the rapid ubiquitylation and subsequent degradation of the target protein. Read more
MScR - Computational modelling to investigate the role of membrane microdomains in cell signalling
The dynamic organization of the plasma membrane into specialized cholesterol-rich microdomains plays a crucial role in cellular signalling and the regulation of various biological processes. Read more
Molecular mechanisms of stem cell function in skeletal muscle ageing
The ability of skeletal muscles to regenerate in response to injury, exercise, growth or disease depends on a population of adult skeletal muscle stem cells. Read more
Interaction between DNA Polymerase theta inhibition and cGAS/STING activation
Emerging evidence suggests that the therapeutic effect of radiotherapy is at least partly dependent upon the induction of an anti-tumour immune response. Read more
Investigating the communication between cancer cells and cells in the tumour microenvironment to improve our understanding of epigenetic regulatory mechanisms and identify new targets for cancer therapy
It is well-established that the molecular mechanisms controlling gene expression are disrupted in cancer cells and work in this area has laid the foundations for targeted cancer therapies. We are interested in the regulatory pathways that control cell proliferation and cell migration and the events that disrupt this control in multiple types of cancer. Read more
MSc by Research: Mechanisms controlling cell ingression through the primitive streak during gastrulation in chick embryos
We investigate the how the key cell behaviours that mediate gastrulation in the early chick embryo. The chick embryo is a model for amniote development including humans. Read more
Cell communication in gastric cancer. MRC GW4 BioMed DTP PhD studentship 2024/25 Entry, PhD in Biosciences
About the GW4 BioMed2 Doctoral Training Partnership. The partnership brings together the Universities of Bath, Bristol, Cardiff (lead) and Exeter to develop the next generation of biomedical researchers. Read more
Live cell imaging of epithelial cancer cell proliferation for therapy
The School of Molecular & Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2023/24. Read more
Understanding apoptotic heterogeneity in cell populations
Apoptosis is a form of programmed cell death that occurs in response to stress such as genomic damage. The decision to initiate apoptosis is taken at the outer mitochondrial membrane (OMM) by members of the Bcl-2 family of proteins. Read more
Hypoxia and HIF signalling in TME as regulators of pro- and anti- tumour-associated immune cell functions (ref: SF22/HLS/APP/GIELING)
Hypoxia (low oxygen tension) and hypoxia-inducible factor (HIF)-1 and HIF-2 signalling are environmental cues on the immune system in both acute and chronic human diseases. Read more
The role of extracellular vesicles in lung epithelial cell communication in health and disease
It is estimated that more than 1 bn people suffer from acute and chronic lung problems resulting in millions of deaths every year. Read more
Barrier functions of the sugary cell coat – Understanding how extracellular signalling proteins and bacterial toxins navigate the cell surface
Are you keen to progress research in glycoscience at the interface between biology, chemistry, and physics?. Glycocalyces are carbohydrate-rich coats surrounding virtually every cell in our body. Read more
Investigate the molecular mechanism controlling FEME (Fast Endophilin Mediated Endocytosis) in directed cancer cell migration using CRISPR, biochemistry, and advanced microscopy methods.
Cancer is a devastating disease. more than one in three people in the UK will develop cancer in their lifetime. Metastasis is the primary cause of cancer related deaths. Read more
