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cell therapy PhD Projects, Programs & Scholarships

We have 92 cell therapy PhD Projects, Programs & Scholarships

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  Gene and Cell Therapy For Muscular Dystrophy, Muscular Atrophy, Diabetes and Metabolic conditions
  Dr K Foster
Applications accepted all year round
Skeletal muscle development is a complex process and a number of regulatory factors for the different steps involved in stem cell activation and proliferation through to multinucleated, post-mitotic cells have been identified.
  Refining haematopoietic stem cell populations and their gene modification as a therapy for rare inherited disorders
  Prof M Malim
Application Deadline: 5 April 2019
Developments from academic and biotech sectors have driven gene and stem cell therapy to the clinical setting, with data demonstrating an encouraging long term safety profile and durable correction of several inherited genetic blood disorders such as ADA-SCID (Strimvelis) and X-CGD (OTL-102).
  Hematopoietic Stem Cell Genetics: Using single cell biology and genetics to understand how hematopoietic stem cells normally sustain blood formation, and how this process is altered during ageing and when leukemia develops.
  Prof Claus Nerlov, Dr P Vyas
Application Deadline: 26 July 2019
Using single cell biology and genetics to understand how hematopoietic stem cells normally sustain blood formation, and how this process is altered during ageing and when leukemia develops.
  Assessing the ability of hypoxic pre-conditioning to enhance the immunomodulatory capacity of canine cardiac stem cell as a bridge to the treatment of dilated cardiomyopathy.
  Dr D Connolly
Applications accepted all year round
Dilated Cardiomyopathy (DCM) is a common and serious disease, which imposes a significant welfare burden in dogs. DCM is particularly well characterise in Dobermans where a 58.8% cumulative prevalence has been identified in European lines.
  CRUK Clinical Research Training Fellowship: developing novel T-cell immunotherapy for paediatric high grade glioma
  Dr K Straathof, Prof D Hargrave, Prof J Anderson
Application Deadline: 27 March 2019
Overall aim of the PhD project is to develop novel T-cell immunotherapy for paediatric high grade glioma. Brain tumours are the major cause of cancer-related death in children, overtaking the other paediatric cancers including leukaemias and other solid tumours.
  The effect of polysialyltransferase modulation on tumour cell migration
  Research Group: Institute of Cancer Therapeutics
  Dr S Shnyder, Dr R Falconer
Applications accepted all year round
One of the main reasons for failure of cancer therapy today is an inability to control tumour dissemination, with secondary tumour deposits the cause of morbidity.
  MRC Precision Medicine DTP: Connecting Molecular Profiles to Phenotype: A Proteomic Resource for Assigning Cell Cycle and Senescent States
  Research Group: Institute of Cell Biology
  Dr T Ly, Dr A Lindqvist
Application Deadline: 8 April 2019
Background. A hallmark of cancer is aberrant cell cycle control leading to pathological cell proliferation. Cell cycle progression is controlled by key kinases, such as cyclin-dependent kinases (CDKs) and polo-like kinases (PLKs).
  Identifying the role of glycosaminoglycans and microglia in early pathology of mucopolysaccharide diseases
  Dr B BIgger, Dr R Holley, Prof S Flitsch
Applications accepted all year round
Mucopolysaccharidoses (MPS) are inherited metabolic disorders caused by the deficiency of specific lysosomal enzymes required for the catabolism of glycosaminoglycans (GAGs) where each MPS type lacks a specific enzyme resulting in the build-up of GAGs in all cells of the body.
  Targeting The Thymus To Improve Immune Recovery Following Stem Cell Transplantation For Cancer Treatment
  Prof G Anderson, Dr W Jenkinson
Applications accepted all year round
Background. The treatment of cancer frequently requires the transplantation of bone marrow to regenerate the immune system that is damaged following ablative therapy.
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