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We have 241 cell signalling PhD Projects, Programmes & Scholarships
cell signalling PhD Projects, Programmes & Scholarships
We have 241 cell signalling PhD Projects, Programmes & Scholarships
Neuronal-Src kinases: oncogenes in brain development and neurodegeneration?
The challenges of the developing human brain include co-ordinating the birth and migration of 100 billion neurons and the formation of their 1000 trillion synaptic connections. Read more
Brainstem circuits in stress-induced changes to behaviour and physiology
A key function of the brain is to constantly monitor our environment – both our surroundings as well as our internal state. As an example, as we eat our stomach distends. Read more
Clock-watchER: Circadian coordination of the plant endoplasmic reticulum
The rotation of the Earth creates periodic day-night changes in environmental conditions such as light and temperature. Organisms are able to adapt to these predictable diurnal cycles through their internal timekeeping system, the circadian clock, which has a periodicity of approximately 24 hours. Read more
CASE: Generating epithelial differentiation models to explore impact of oral mucosal immunity on EBV replication
Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus1 associated with the development of both lymphoid and epithelial tumours; and most recently, implicated in the development of autoimmune diseases such as MS, ME and long covid2. Read more
(Bicentenary) Modelling the effects of dopaminergic neuromodulation on brain state and function
Dopamine is an essential neurotransmitter that influences various physiological functions such as motor control, as well as adaptive behaviour through salience and novelty processing, which in turn support attention, exploration, and goal-directed behaviour (Cools, 2019; Shohamy & Adcock; 2010). Read more
(Bicentenary) Circadian Tick-Talking in the metabolic clock: The role of Dorsomedial Cholecystokinin neurons in the circadian regulation of metabolic activity
Our daily or circadian body clock is one of the most important timing systems in our brain and body, ensuring that our brain’s activity is appropriately aligned with our homeostatic, physiological, and behavioural needs across the day. Read more
(Bicentenary) Super-resolution proximity nucleotide labelling
The spatiotemporal coordination of biomolecular interactions is fundamental to every known biological process. Read more
CSC studentship: Understanding human sulfatases involved in heparan sulfate degradation
Various types of carbohydrates, or sugars, are ubiquitous throughout nature and perform a number of important functions in our cells. Read more
(VIDA DTC) Do altered oligodendrocyte-microglial interactions underlie global white matter tract impairments and cognitive decline after focal ischaemic stroke?
Research Group:
Centre for Discovery Brain Sciences
VIDA (Vascular and Immune contributors to DementiA) is a new multi-institutional partnership between Alzheimer’s Society and four world-leading research sites. Read more
Designing microbial co-cultures for the production of biocontrol solutions (C3.5-CMB-Pandhal)
Engineering biology through co-cultivation of microorganisms is an emerging area of synthetic biology, it can also help in understanding microbial interactions and their ecological roles, but also to create new and novel products. Read more
A new imaging approach to unravel the mysteries of extracellular vesicle journey through tissues: merging chemistry, microscopy, and molecular biology to track information flow at nanoscale (C3.5-DEN-Lambert)
Extracellular vesicles (EVs) are complex cell-derived nano-vesicular structures that drive a multitude of biological responses. EVs carry a range of bioactive molecules, including DNA, RNA, proteins, glycans and metabolites, which generate responses in surrounding cells to maintain tissue function. Read more
The antiviral roles of ISG15 modifications
One of the most important challenges facing biomedical research is to understand the molecular details of how our immune system defends against pathogens. Read more
Investigating a polarity switch in bird wing feather development
The evolution of flight in birds is one of the most extraordinary events in natural history. A fundamental event was the formation of feathers, which first appeared in flightless ancestral theropod dinosaurs. Read more
Funded PhD - Investigating the effects of diabetes and obesity medications on body fluid homeostasis
The increasing prevalence of obesity and diabetes constitutes a major threat to public health. Until recently, such diseases were only seen in adults but are also now occurring more frequently in children. Read more
A foundation model for C elegans brain dynamics
AI_CDT_DecisionMaking. Details. Neuroscience techniques for interfacing with brains have dramatically improved in the last two decades. Read more