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We have 241 cell signalling PhD Projects, Programmes & Scholarships
cell signalling PhD Projects, Programmes & Scholarships
We have 241 cell signalling PhD Projects, Programmes & Scholarships
Investigating the roles that G protein coupled receptors play in hypertension
G protein-coupled receptors (GPCRs) constitute a very large family of heptahelical, integral membrane proteins that mediate a wide variety of physiological processes ranging from the transmission of light and odorant signals to the mediation of neurotransmission and hormonal actions. Read more
Investigating the effect of stress hormones in Chronic Lymphocytic Leukaemia
Applications are invited for a 3-year funded PhD studentship at Brighton and Sussex Medical School. Project details. Chronic Lymphocytic Leukaemia (CLL) is the most common leukaemia in the UK. Read more
(VIDA DTC) Unblocking blood vessel occlusion in dementia: Mechanisms of thrombi extrusion and removal
Microthrombi formation and occlusion of brain blood vessels is a surprisingly common feature of the aging brain (>30%) and is recognised as a key contributor to Alzheimer’s disease/dementia. Read more
Beyond Lysine: Exploring the Functional Consequences of Non-Canonical Ubiquitination in Health and Disease
Ubiquitination is a fundamental post-translational modification (PTM) crucial for a wide range of cellular processes, including protein degradation, localization, quality control, DNA repair, cell signalling, and immune responses. Read more
Molecular mechanisms underlying Parkinson's disease
There is great need for improved understanding of the mechanistic biology underlying Parkinson’s disease. Such knowledge will help with development of new drugs that slow or even halt the progression of the disease. Read more
China Scholarship Council: Deciphering molecular pathways underlying Parkinson's disease
There is great need for improved understanding of the mechanistic biology underlying Parkinson’s disease. Such knowledge will help with development of new drugs that slow or even halt the progression of the disease. Read more
Utrasound as a healing modality for oral tissue
Project description. Low intensity pulsed ultrasound (LIPUS) is used clinically in bone fracture clinics to promote wound healing and has been shown experimentally to promote cell migration with potential for wound healing. Read more
Determining metabolic reprogramming events in stem cells in response to inflammatory disease phenotype
Mesenchymal stem cells (MSCs) are responsible for the repair of damaged tissue following injury and disease as well as moderating innate and adaptive immune responses and regulation of self-tolerance and tissue homeostasis. Read more
Electrifying Cells! Exploring the role of bioelectronic stimulation and bioelectric signalling, with a focus on influencing stem cell behaviour
Electrical stimulation of cells and tissues has been observed to help with healing processes, for example in bone regeneration. Within the NHS, some fracture clinics use electrical stimulation as a to promote healing, often when other methods fail. Read more
Mathematical Modelling of Cell Shape and Localised Cell growth.
The correct cell shape is essential for proper cell function. For example, in the brain signalling between neurons is received by dendritic spines, Dendritic spines are protrusions on the surface of the neuron, they come in different shapes, the most well-known being mushroom shaped. Read more
Precision Medicine DTP - Defining vascular-immune cell heterogeneity and and intercellular communication in human vascular disease and dementia
About the Project. Additional supervisor - Prof. Raj Kalaria (Newcastle University). Background. Dementia, affecting nearly 1 million people in the UK, leads to progressive cognitive decline and impairment in daily activites. Read more
Last chance to apply
MRC DiMeN Doctoral Training Partnership: Targeting the cytoplasmic regulators of androgen receptor signalling in prostate cancer
Background. Steroid receptor signalling is critical in hormone driven cancers such as prostate cancer, which accounts for >11,000 deaths annually, in the UK. Read more
MSc by Research: Investigation of the interplay between the cell cycle and Notch intracellular domain levels in presomitic mesoderm cells in somitogenesis
One of the key processes in embryo development is somitogenesis. This is the formation of segments, known as somites, that go on to develop into bone and skeletal muscle. Read more
EASTBIO: Proteomic Analysis of Leptin and Its Bioactive Fragments: Implications for Leptin Receptor Function in Health and Disease
The hormone leptin plays a crucial role in regulating body weight by signalling satiety and energy balance to the brain. Emerging research has also implicated reduced leptin signalling in the increased risk of developing neurological disorders, including Alzheimer’s Disease. Read more
Peptidomimetic Inhibitors of Protein-Protein Interactions – A Sustainable Approach
Transient protein-protein interactions (PPIs) control all cellular processes (e.g. mitosis) (1) relevant to health and disease. Read more